ReviewJournal of the National Cancer Center2026
Light-responsive nanotherapeutic carbon dots: a next generation tool for cancer phototherapy.
Review in Journal of the National Cancer Center, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Review
- Advances in green-synthesized quantum dot-based nanoplatforms for cancer treatment, photodynamic therapy, photothermal therapy and cancer theranostics.RSC advances · 2026Review
- Cancer-Associated Fibroblast-Targeted Nanomedicine in Solid Tumor Therapy: From Mechanisms of Therapeutic Resistance to Precision Stromal Modulation.International journal of nanomedicine · 2026Review
- A Simulation Study of Carbon Dot-Assisted Photothermal Heating in Tumor Tissue.Journal of medical physicsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carbon dots (CDs) have emerged as promising nanomaterials in cancer phototherapy due to their unique optical properties, biocompatibility, and tunability. This review comprehensively examines the role of CDs in photodynamic therapy (PDT) and photothermal therapy (PTT), highlighting their mechanisms of action, including the induction of apoptosis, necrosis, and necroptosis in cancer cells. Key factors influencing the efficacy of cancer phototherapy-such as the tumor microenvironment (TME), nanoparticle stability, and light parameters-are thoroughly analyzed. Advancements in surface modifications, targeted, drug delivery and multifunctional applications, including their integration with chemotherapy and immunotherapy, further expand the clinical potential of CDs. While preclinical studies have demonstrated the efficacy of CDs in selectively targeting cancer cells and inducing therapeutic effects, challenges related to biosafety and regulatory approval hinder clinical translation. By addressing existing challenges and leveraging interdisciplinary innovations, CDs hold great promise for personalized and less invasive cancer treatments. Their future success in clinical application will depend on overcoming biological barriers and optimizing the safety profile to facilitate their seamless integration into oncology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.