Evidence map›Paper›PMID 41738010›Full record

ArticleImaging neuroscience (Cambridge, Mass.)

Multiple partially overlapping neural modules orchestrate conflict processing.

Melinda Sabo, Manuel Varlet, Edmund Wascher, Patrick D Gajewski, Tijl Grootswagers

Registry-linked trialAbstract read
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05155397 (The Dortmund Vital Study), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05155397 active not recruitingnot on this map

The Dortmund Vital Study: Impact of Biological and Lifestyle Factors on Cognitive Performace and Work Ability Across the Lifespan. An Interdisciplinary, Cross-sectional and Longitudinal Study

TypeobservationalSponsorTechnical University of DortmundRan2016 to 2037Enrolled627ConditionsAge-related Cognitive Decline
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Melinda SaboLeibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany.ORCID https://orcid.org/0000-0001-8585-7115
Manuel VarletThe MARCS Institute for Brain, Behaviour and Development, Western Sydney University, Sydney, Australia.ORCID https://orcid.org/0000-0001-5772-2061
Edmund WascherLeibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany.ORCID https://orcid.org/0000-0003-3616-9767
Patrick D GajewskiLeibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany.ORCID https://orcid.org/0000-0001-8240-1702
Tijl GrootswagersThe MARCS Institute for Brain, Behaviour and Development, Western Sydney University, Sydney, Australia.ORCID https://orcid.org/0000-0002-7961-5002

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive conflict is a ubiquitous aspect of our daily life, yet its underlying neural mechanisms remain debated. Competing theories propose that conflict processing is governed by either a domain-general system, multiple conflict-specific modules, or an architecture involving partially overlapping mechanisms. The aim of the current study was to clarify how these mechanisms operate at the neural level using a data-driven decoding approach. We analyzed electroencephalogram (EEG) data from 507 healthy participants (ages 20-70) from the Dortmund Vital Study (ClinicalTrials.gov NCT05155397) who completed three conflict tasks: a Change Detection task, a Simon task, and a Stroop task. Using multivariate decoding to distinguish conflict from non-conflict trials, we observed robust within-task decoding across all tasks. However, cross-task decoding revealed shared conflict representations only in specific task pairs. These findings support an account in which conflict processing relies on partially overlapping neural mechanisms rather than being fully domain-general or entirely task specific. We argue that conflict-related neural processes might be best conceptualized as a continuum of overlap and differentiation, with domain-generality and domain-specificity representing the endpoints of this spectrum.

Indexed as

attentioncognitive controldecodingEEGSimon taskStroop task

Identifiers

PMID41738010
PMCPMC12926776

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.