Evidence map›Paper›PMID 41738001›Full record

ArticleTherapeutic advances in reproductive health

A mixed-method analysis of health literacy and indicators of well-being in women with polycystic ovary syndrome across the lifespan.

Crystal C Douglas, Ahmar Hashmi, Alexis Mclain, Emily J Arentson-Lantz

Registry-linked trialAbstract read
In one paragraph

Article in Therapeutic advances in reproductive health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05769426 (Health Risks and Barriers to Management Across the PCOS Lifespan), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05769426 completednot on this map

Health Risks and Barriers to Management Across the PCOS Lifespan

TypeobservationalSponsorThe University of Texas Medical Branch, GalvestonRan2023 to 2024Enrolled49ConditionsPolycystic Ovary Syndrome, Menopause
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Crystal C DouglasDepartment of Nutrition Sciences and Health Behavior, University of Texas Medical Branch, Galveston, TX, USA.ORCID https://orcid.org/0000-0003-0354-1913
Ahmar HashmiDepartment of Nutrition Sciences and Health Behavior, University of Texas Medical Branch, Galveston, TX, USA.ORCID https://orcid.org/0000-0002-1592-0606
Alexis MclainDepartment of Nutrition Sciences and Health Behavior, University of Texas Medical Branch, Galveston, TX, USA.
Emily J Arentson-LantzDepartment of Nutrition Sciences and Health Behavior, University of Texas Medical Branch, Galveston, TX 77555-1124, USA.ORCID https://orcid.org/0000-0001-7303-8067

Funding

UTMB CTSA: Greater Gulf Coast Translational Science AllianceUM1TR005443 · NCATS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Randall J Urban · 2025 to 2026
$8.3M
NCATS NIH HHS UM1 TR005443
6 · The paper itself

Abstract

Background: Despite the severe, chronic nature of polycystic ovary syndrome (PCOS), relatively little is known about the lived experience of women with this condition, especially as they transition through menopause. Objective: This mixed-methods study investigated the lived experience of women with PCOS before and after the menopause transition to understand their health literacy, barriers to healthcare management, and desired resources to improve their health and well-being. Design: This was a convergent-parallel mixed-methods study. Methods: Twenty-four participants completed semi-structured interviews and electronic surveys between April 2023 and August 2024. Qualitative data were analyzed using an inductive open-ended approach for thematic analysis. Results: Participants, including 17 pre-menopausal (30.1 ± 4.8 years) and 7 post-menopausal (58.6 ± 6.0 years), self-reported clinical symptoms of PCOS (irregular cycles, hirsutism, and acne) and higher than average anxiety symptoms (pre-menopausal only). Both pre- and post-menopausal women were knowledgeable about the impact of PCOS on their fertility, and expressed low to moderate health literacy to successfully manage the PCOS-related symptoms. Few participants expressed understanding of long-term chronic disease risk. Pre-menopausal participants sought resources for managing symptoms but reported dissatisfaction with provider education and overall patient care. Post-menopausal participants did not view a PCOS diagnosis as a health concern following menopause and internalized PCOS-related health issues as something to be endured. Both pre- and post-menopausal women expressed desires for improved personalized care, life-stage-specific support groups, and better patient-facing resources. Conclusion: Pre-menopausal and post-menopausal women with PCOS exhibit low health literacy about the potential impact of PCOS on metabolic health. Primary care providers should be trained in how to educate women with PCOS, with an emphasis on the impact of the disease beyond reproductive health and through the lifespan. In addition, creating patient-centered resources supporting women throughout the lifespan is needed. Trial registration: This study was registered with ClinicalTrials.gov as NCT05769426.

Indexed as

agingfemalehyperandrogenismmenopausePCOS

Identifiers

PMID41738001
PMCPMC12926541

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.