Evidence map›Paper›PMID 41737807›Full record

ArticleGastroenterology report2026

Associations between parenteral energy or amino acid doses and clinical outcomes in fasting patients undergoing gastroenterological cancer surgery: a nationwide cohort study using real-world data.

Yoshikuni Kawaguchi, Kenta Murotani, Nahoki Hayashi, Satoru Kamoshita

Abstract read
In one paragraph

Article in Gastroenterology report, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Reply to: "Amino acid strategy in early postoperative parenteral nutrition".JPEN. Journal of parenteral and enteral nutrition · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yoshikuni KawaguchiHepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Kenta MurotaniSchool of Medical Technology, Kurume University, Fukuoka, Japan.
Nahoki HayashiMedical Affairs Department, Research and Development Center, Otsuka Pharmaceutical Factory, Inc, Tokyo, Japan.
Satoru KamoshitaMedical Affairs Department, Research and Development Center, Otsuka Pharmaceutical Factory, Inc, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to investigate the associations between parenteral energy/amino acid doses and clinical outcomes in patients who were fasting after gastroenterological cancer surgery. Methods: Patients who were fasting for ≥ 7 days after gastroenterological cancer surgery between 2011 and 2022 were identified in a Japanese medical claims database. The associations between parenteral energy/amino acid doses which are supplied to patients via the peripheral or central vein and clinical adverse events were investigated. Low- (< 0.8 g/kg/day) and high- (≥ 0.8 g/kg/day) amino acid dose groups were compared using propensity score matching (PSM). The primary outcome was clinical adverse events, and secondary outcomes were in-hospital mortality, postoperative complications, decline in activities of daily living, rehospitalization, length of hospital stay, and hospitalization costs. Results: Of 18,294 eligible patients, no association was found between clinical adverse events and energy doses (Wald test, Conclusions: Parenteral amino acid dosing may play an important role in improving clinical outcomes in patients after gastroenterological cancer surgery, particularly in those who are fasting for 7 days or longer.

Indexed as

amino acidsclinical outcomeenergygastroenterological cancer surgeryparenteral nutritionreal-world data

Identifiers

PMID41737807
PMCPMC12927415

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.