Evidence map›Paper›PMID 41737645›Full record

ArticleJCEM case reports2026

Fatal tracheal perforation following Dabrafenib-Trametinib therapy in

Antonio Matrone, Marianna Scordo, Elisa Minaldi, Liborio Torregrossa, Gabriele Materazzi, Rossella Elisei

Abstract readCase Reports
In one paragraph

Article in JCEM case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Antonio MatroneUnit of Endocrinology, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa 56124, Italy.ORCID https://orcid.org/0000-0003-4263-4717
Marianna ScordoUnit of Endocrinology, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa 56124, Italy.
Elisa MinaldiUnit of Endocrinology, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa 56124, Italy.
Liborio TorregrossaPathology Unit 3, Department of Surgical, Medical, Molecular Pathology and Critical Area, University Hospital of Pisa, Pisa 56126, Italy.
Gabriele MaterazziEndocrine Surgery Unit, Department of Surgical, Medical, Molecular Pathology and Critical Area, University Hospital of Pisa, Pisa 56126, Italy.
Rossella EliseiUnit of Endocrinology, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Pisa 56124, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anaplastic thyroid cancer (ATC), pure or mixed, is the most aggressive form of thyroid cancer that leads to rapid death if left untreated.

Indexed as

adverse eventsanaplastic thyroid cancerBRAF V600Edabrafenibperforationtrametinib

Identifiers

PMID41737645
PMCPMC12926218

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.