Evidence map›Paper›PMID 41737513›Full record

ArticleJournal of contemporary brachytherapy2025

Precision brachytherapy for bulky cervical tumors: Clinical implementation of a 3D-printed template and curved needle system.

Yuanjie Cao, Imashi Sandupama Wickramage, Chen Li, Youheng Tan, Qingsong Pang, Jie Chen

Abstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuanjie CaoDepartment of Radiation Oncology, Tianjin Medical University Cancer Institute & Hospital, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin's Clinical Research Center for Cancer, National Clinical Research Center for Cancer, Tianjin 300060, China.
Imashi Sandupama WickramageDepartment of Radiation Oncology, Tianjin Medical University Cancer Institute & Hospital, Tianjin Medical University, Tianjin 300060, China.
Chen LiDepartment of Radiation Oncology, Tianjin Medical University Cancer Institute & Hospital, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin's Clinical Research Center for Cancer, National Clinical Research Center for Cancer, Tianjin 300060, China.
Youheng TanSchool of Automation, Central South University, Changsha, Hunan 410083, China.
Qingsong PangDepartment of Radiation Oncology, Tianjin Medical University Cancer Institute & Hospital, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin's Clinical Research Center for Cancer, National Clinical Research Center for Cancer, Tianjin 300060, China.
Jie ChenDepartment of Radiation Oncology, Tianjin Medical University Cancer Institute & Hospital, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin's Clinical Research Center for Cancer, National Clinical Research Center for Cancer, Tianjin 300060, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Locally advanced cervical cancer (LACC) in bulky tumors and parametrial invasion poses substantial challenges for effective brachytherapy, often resulting in sub-optimal target coverage and increased risk for adjacent organs. This study evaluated the clinical feasibility, dosimetric performance, and early outcomes of a novel high-dose-rate brachytherapy strategy using patient-specific 3D-printed templates and curved flexible needles in LACC. Material and methods: We retrospectively analyzed 20 patients with stage IIIB-IVB cervical cancer treated between July 2023 and August 2024. All patients received pelvic intensity-modulated radiotherapy and concurrent cisplatin-based chemotherapy, followed by brachytherapy Results: The mean high-risk clinical target volume (HR-CTV) was V Conclusions: The integration of 3D-printed templates and curved flexible needles enables precise and individualized brachytherapy for bulky and parametrial invasive cervical cancer, achieving high target conformity and effective organ sparing. This approach demonstrates promising early efficacy and safety, supporting its potent advanced solution for complex LACC cases.

Indexed as

3D printingbrachytherapycervical cancerdosimetryflexible needlesorgan sparing

Identifiers

PMID41737513
PMCPMC12928130

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.