Indene and indole-based compounds as potential antimicrobial agents: synthesis, activity, docking studies and ADME analysis.

Vilma Lovrinčević, Monika Šabić Runjavec, Nikica Baričević, Ines Despotović, Jerome Le-Cunff, Dragana Vuk, Marija Vuković Domanovac

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Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vilma LovrinčevićDepartment of Organic Chemistry, University of Zagreb Faculty of Chemical Engineering and Technology Trg Marka Marulića 19 HR-10000 Zagreb Croatia dvuk@fkit.unizg.hr.

Monika Šabić RunjavecDepartment of Industrial Ecology, University of Zagreb Faculty of Chemical Engineering and Technology Trg Marka Marulića 19 HR-10000 Zagreb Croatia mvukovic@fkit.unizg.hr.ORCID https://orcid.org/0000-0002-5040-6995

Nikica BaričevićDepartment of Organic Chemistry, University of Zagreb Faculty of Chemical Engineering and Technology Trg Marka Marulića 19 HR-10000 Zagreb Croatia dvuk@fkit.unizg.hr.ORCID https://orcid.org/0009-0009-4762-4412

Ines DespotovićDivision of Physical Chemistry, Ruđer Bošković Institute Bijenička cesta 54 HR-10000 Zagreb Croatia.ORCID https://orcid.org/0000-0003-3427-6534

Jerome Le-CunffXellia Ltd Slavonska Avenija bb 10000 Zagreb Croatia.

Dragana VukDepartment of Organic Chemistry, University of Zagreb Faculty of Chemical Engineering and Technology Trg Marka Marulića 19 HR-10000 Zagreb Croatia dvuk@fkit.unizg.hr.ORCID https://orcid.org/0000-0002-1626-599X

Marija Vuković DomanovacDepartment of Industrial Ecology, University of Zagreb Faculty of Chemical Engineering and Technology Trg Marka Marulića 19 HR-10000 Zagreb Croatia mvukovic@fkit.unizg.hr.ORCID https://orcid.org/0000-0001-5818-7347

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The excessive use of antibiotics in recent years has led to an accelerated development of resistance in bacterial pathogens and thus to one of the greatest problems of our time: antibiotic resistance. Therefore, despite the large number of available drugs, the development of new and structurally diverse antibiotics is urgently needed. In this study, various indole and indene derivatives were prepared and characterised and their antibacterial activity against Gram-positive bacteria

Identifiers

PMID41737448

DOI10.1039/d5ra08239k

PMCPMC12928186

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.