ArticleCJC open2026
Improving Stress Echocardiography for Enhanced Detection of Left Main and Multivessel Coronary Artery Disease.
Article in CJC open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
Background: Stress echocardiography (SE) is a well established method for diagnosing and assessing coronary artery disease (CAD). However, accurately identifying high-risk patients remains a challenge. The aim of the study is to explore the potential of novel predictors to enhance the diagnostic precision of SE for detecting left-main or triple-vessel CAD. Methods: We included consecutive patients who underwent invasive coronary angiography within 6 months of SE between January 2018 and April 2022. Traditional high-risk SE features included extensive wall-motion abnormalities, a reduction in left ventricular ejection fraction Results: Of the 257 patients (mean age 66 ± 9 years) included in the analysis, 53 (21%) had high-risk CAD. Multivariate analyses identified traditional high-risk SE features, as well as ≥ 5% absolute reduction in GLS, as independent predictors of high-risk anatomy. Integrating Conclusions: In a real-world cohort, adding the change in GLS with exercise stress can improve the performance of SE for the detection of high-risk CAD.
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