Evidence map›Paper›PMID 41737154›Full record

ArticlePakistan journal of medical sciences2026

Efficacy of spleen aminopeptide combined with budesonide nebulization in the treatment of pediatric bronchial asthma and its impact on immune function and inflammatory cytokines.

Su He, Ning Ran, Xu Yang, Bing Zhu, Dan Zhou

Abstract read
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In one paragraph

Article in Pakistan journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Su HeSu He, Department of Respiratory, Baoding Hospital, Key Laborary of Clinical Research on Respiratory Digestive Disease, Beijing Children's Hospital Affiliated to Capital Medical University, Baoding 071000, Hebei, China.
Ning RanNing Ran, Department of Respiratory, Baoding Hospital, Key Laborary of Clinical Research on Respiratory Digestive Disease, Beijing Children's Hospital Affiliated to Capital Medical University, Baoding 071000, Hebei, China.
Xu YangXu Yang, Department of Respiratory, Baoding Hospital, Key Laborary of Clinical Research on Respiratory Digestive Disease, Beijing Children's Hospital Affiliated to Capital Medical University, Baoding 071000, Hebei, China.
Bing ZhuBing Zhu, Department of Respiratory, Baoding Hospital, Key Laborary of Clinical Research on Respiratory Digestive Disease, Beijing Children's Hospital Affiliated to Capital Medical University, Baoding 071000, Hebei, China.
Dan ZhouDan Zhou, Department of Respiratory, Baoding Hospital, Key Laborary of Clinical Research on Respiratory Digestive Disease, Beijing Children's Hospital Affiliated to Capital Medical University, Baoding 071000, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the clinical efficacy of spleen aminopeptide(SAP) combined with budesonide nebulization(BN) in the treatment of pediatric bronchial asthma, and its impact on the immune function and inflammatory cytokines of the affected population. Methodology: This was a retrospective study. A total of 120 children with bronchial asthma admitted to Baoding Hospital, Beijing Children's Hospital Affiliated to Capital Medical University from December 2022 to October 2024 were enrolled and randomly divided into the control group(received symptomatic treatment along with BN) and study group(received additional oral SAP based on the control group regimen), with 60 cases in each group. After treatment, the clinical efficacy, adverse drug reaction(ADR) rate, changes in immune markers, and inflammatory cytokines were compared between the two groups. Results: The overall response rate was 93% in the study group and 78% in the control group, with a statistically significant difference( Conclusion: The combination therapy using SAP and BN demonstrates significant clinical efficacy in treating pediatric bronchial asthma. SAP plus BN can effectively enhance immune function and reduce levels of inflammatory cytokines without significantly increasing adverse reactions.

Indexed as

BudesonideImmune functionInflammatory cytokinesPediatric bronchial asthmaSpleen aminopeptide

Identifiers

PMID41737154
PMCPMC12927119

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.