Evidence map›Paper›PMID 41737143›Full record

ArticleJournal of osteoporosis2026

Relationship of Preexisting Vertebral Fractures and Endplate Injury to Intervertebral Bridging Ossification After Balloon Kyphoplasty for Osteoporotic Vertebral Fractures.

Toshiaki Maruyama, Naosuke Kamei, Toshio Nakamae, Yoshinori Fujimoto, Kiyotaka Yamada, Kazuto Nakao, Fadlyansyah Farid, Hiroki Fukui, Nobuo Adachi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of osteoporosis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Toshiaki MaruyamaDepartment of Orthopaedic Surgery, JA Hiroshima General Hospital, Hatsukaichi, Japan, hirobyo.jp.ORCID https://orcid.org/0009-0008-7160-2945
Naosuke KameiDepartment of Orthopaedic Surgery, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan, miyazaki-u.ac.jp.ORCID https://orcid.org/0000-0001-5076-0145
Toshio NakamaeDepartment of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, hiroshima-u.ac.jp.ORCID https://orcid.org/0000-0002-9790-3884
Yoshinori FujimotoDepartment of Spine and Spinal Cord Surgery, Amano Rehabilitation Hospital, Hatsukaichi, Japan.ORCID https://orcid.org/0009-0009-6142-0467
Kiyotaka YamadaDepartment of Spine and Spinal Cord Surgery, Amano Rehabilitation Hospital, Hatsukaichi, Japan.ORCID https://orcid.org/0009-0005-3883-9826
Kazuto NakaoDepartment of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, hiroshima-u.ac.jp.ORCID https://orcid.org/0009-0009-8569-7030
Fadlyansyah FaridDepartment of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, hiroshima-u.ac.jp.ORCID https://orcid.org/0000-0002-1719-6527
Hiroki FukuiDepartment of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, hiroshima-u.ac.jp.ORCID https://orcid.org/0009-0005-6406-135X
Nobuo AdachiDepartment of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan, hiroshima-u.ac.jp.ORCID https://orcid.org/0000-0002-5570-3729

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Intervertebral bridging ossification (IBO) occasionally occurs after balloon kyphoplasty (BKP) for osteoporotic vertebral fractures (OVFs), contributing to stabilization. However, the predisposing factors remain unclear. This study aimed to identify preoperative factors associated with IBO formation. Methods: This was a retrospective cohort study of patients who underwent BKP for OVFs. Radiological evaluations included the location of the fractured vertebra, number of preexisting vertebral fractures, endplate damage, intervertebral disc injury, presence of diffuse idiopathic skeletal hyperostosis, lateral wedge angle and regional kyphosis angle, and were assessed using radiography, computed tomography and magnetic resonance imaging (MRI). Clinical outcomes were evaluated via the visual analogue scale (VAS) and Oswestry Disability Index (ODI) preoperatively and at 1 month and 1 year postoperatively. Results: Patients with IBO showed higher rates of thoracolumbar junction fractures (T11-L1) ( Conclusion: Preexisting vertebral fractures and proximal endplate injury are key predictors of IBO formation after BKP. Although associated with higher short-term pain, IBO appears to contribute to long-term stabilization and pain relief, providing insights into postoperative outcomes and treatment strategies.

Indexed as

balloon kyphoplastybridging ossificationendplate injuryosteoporosisvertebral

Identifiers

PMID41737143
PMCPMC12927987

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.