Evidence map›Paper›PMID 41737116›Full record

ArticleCureus2026

When Thyrotoxicosis Meets a Latent Plaque: Unmasking a Type I Myocardial Infarction.

Joseph Muñoz, Damini Kashyap, Aleksandr Kouk, Thomas Greco, Joseph Maslak

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph MuñozInternal Medicine, HCA Citrus Hospital, Inverness, USA.
Damini KashyapInternal Medicine, HCA Citrus Hospital, Inverness, USA.
Aleksandr KoukInternal Medicine, HCA Citrus Hospital, Inverness, USA.
Thomas GrecoInternal Medicine, HCA Citrus Hospital, Inverness, USA.
Joseph MaslakInternal Medicine, HCA Citrus Hospital, Inverness, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyrotoxicosis is a rare but significant precipitant of acute coronary syndrome (ACS), especially in young individuals without traditional cardiovascular risk factors. We present the case of a 36-year-old male with no past medical history who arrived with substernal chest pain, elevated troponins, and sinus rhythm without ST changes on ECG. Thyroid ultrasound revealed a large goiter, and labs confirmed severe thyrotoxicosis. Coronary angiography showed 85% stenosis of the proximal-to-mid left anterior descending artery, managed successfully with stent placement. This case demonstrates how an excess of thyroid hormone may contribute to the development of type I myocardial infarction. Thyrotoxicosis should be included in the differential diagnosis of ACS in young patients without traditional risk profiles to ensure timely diagnosis and targeted therapy.

Indexed as

acute coronary syndromenstemi type 1plaque rupturesubclinical atherosclerosisthyrotoxicosis

Identifiers

PMID41737116
PMCPMC12928174

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.