ArticleCureus2026
Slot-Based Antimicrobial Low-Cost Non-surgical Periodontal Therapy in the Management of Periodontitis: A Case Series and Narrative Review.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periodontitis is a chronic infectious and inflammatory disease characterized by progressive destruction of the periodontal ligament and alveolar bone. While scaling and root planing (SRP) remains the cornerstone of non-surgical periodontal therapy, mechanical debridement alone may be inadequate in cases with deep periodontal pockets and persistent microbial reservoirs. In the context of periodontitis, "slot-based therapy" refers to a comprehensive anti-infective treatment strategy based on pathogen-directed antimicrobial principles and low-cost periodontal care concepts, combining mechanical debridement with adjunctive antimicrobial measures in a simplified, cost-effective, and evidence-based approach, particularly suited to resource-limited clinical settings. This article presents a case series of three patients with localized and generalized periodontitis who were managed using non-surgical slot therapy protocols. All patients exhibited varying degrees of gingival inflammation, plaque accumulation, and compromised periodontal health at baseline. Treatment involved ultrasonic SRP supplemented with adjunctive antiseptic-based antimicrobial strategies, including povidone-iodine subgingival irrigation and dilute sodium hypochlorite rinses for maintenance, with systemic antimicrobials prescribed selectively based on clinical indication. Clinical follow-up demonstrated a consistent reduction in gingival inflammation, improved gingival contour, and enhanced periodontal health across all three cases. No adverse effects were observed during the treatment or follow-up periods. The outcomes observed in this case series support the clinical utility of slot therapy as a pragmatic adjunct to conventional non-surgical periodontal treatment, offering a viable alternative to technology-dependent modalities while achieving meaningful clinical improvement.
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