ArticleCureus2026
Enteroviral Meningitis-Associated Respiratory Deterioration in a Neonate Treated With High-Flow Nasal Cannula Therapy.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enteroviral meningitis is a common cause of aseptic meningitis in infants, yet respiratory deterioration, including central hypoventilation, is seldom emphasized. High-flow nasal cannula (HFNC) therapy may offer benefits beyond oxygen delivery. We report a case of a six-day-old term boy with enteroviral meningitis caused by coxsackievirus B2. He developed intermittent oxygen desaturation, bradypnea, and hypercapnia that were unresponsive to standard oxygen supplementation. HFNC rapidly stabilized his respiratory rate and oxygen saturation. This case suggests that HFNC may be a useful noninvasive option for central hypoventilation in viral meningitis. Its potential mechanisms include providing mild positive airway pressure, reducing dead space, and influencing central respiratory drive. Early recognition and timely initiation of HFNC could help prevent intubation and mechanical ventilation in similar cases.
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