Evidence map›Paper›PMID 41737052›Full record

ArticleFrontiers in artificial intelligence2026

The realism of behavioral theory-based vs. non-theory-based AI agents during a simulated infant formula shortage.

Linda Desens, Brandon Walling, Rhys O'Neill, Vanessa Howard, Mary Giammarino, Denise Scannell, Anya Kemble, Taylor Wilkerson, Nyalok Nhial, Sara Beth Elson and 1 more

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In one paragraph

Article in Frontiers in artificial intelligence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Linda DesensThe MITRE Corporation, McLean, VA, United States.
Brandon WallingThe MITRE Corporation, McLean, VA, United States.
Rhys O'NeillThe MITRE Corporation, McLean, VA, United States.
Vanessa HowardThe MITRE Corporation, McLean, VA, United States.
Mary GiammarinoThe MITRE Corporation, McLean, VA, United States.
Denise ScannellThe MITRE Corporation, McLean, VA, United States.
Anya KembleThe MITRE Corporation, McLean, VA, United States.
Taylor WilkersonThe MITRE Corporation, McLean, VA, United States.
Nyalok NhialThe MITRE Corporation, McLean, VA, United States.
Sara Beth ElsonThe MITRE Corporation, McLean, VA, United States.
Scott RosenThe MITRE Corporation, McLean, VA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: AI-driven digital twins and autonomous AI agents are increasingly used to simulate human behavior during crises. Incorporating behavioral science frameworks may improve agent realism, but this practice is still in its infancy. This research evaluates the realism of behavioral theory-based agents in a controlled experimental design. Methods: Using a simulated infant formula shortage in South Dallas County, we compare two conditions: one with theory-based agents, and another without. Participants (human raters) assessed the perceived realism of agent decisions across both conditions. Results: Results showed significantly higher realism ratings for the theory-based agents, supporting our hypothesis. Discussion: This study constitutes an early effort to assess behavioral theory in simulation frameworks and establish a repeatable method for assessing behavioral fidelity. It provides policymakers and researchers with a theory-informed approach for enhancing AI agent realism, with the goal of increasing trust in digital twin models used for decision support in high-stakes environments.

Indexed as

agentic AIAI agentAI agent validationautonomous agentsbehavioral theorydigital twins

Identifiers

PMID41737052
PMCPMC12926465

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.