Evidence map›Paper›PMID 41736957›Full record

ArticleDEN open2026

Utility of Hybrid Endoscopy Combining Small-Bowel Capsule Endoscopy and Conventional Ileocolonoscopy in Crohn's Disease.

Takahiro Ito, Kohei Matsunaga, Yuya Ohno, Muchir Shi, Atsuo Maemoto

Abstract read
In one paragraph

Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Takahiro ItoInflammatory Bowel Disease Center Sapporo Higashi Tokushukai Hospital Hokkaido Japan.ORCID https://orcid.org/0000-0001-5228-4840
Kohei MatsunagaInflammatory Bowel Disease Center Sapporo Higashi Tokushukai Hospital Hokkaido Japan.
Yuya OhnoInflammatory Bowel Disease Center Sapporo Higashi Tokushukai Hospital Hokkaido Japan.
Muchir ShiInflammatory Bowel Disease Center Sapporo Higashi Tokushukai Hospital Hokkaido Japan.
Atsuo MaemotoInflammatory Bowel Disease Center Sapporo Higashi Tokushukai Hospital Hokkaido Japan.ORCID https://orcid.org/0000-0002-9182-8502

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To evaluate the safety and utility of hybrid endoscopy for whole-bowel assessment in Crohn's disease (CD) and its role in treatment decision-making. Methods: This single-center retrospective study included 125 patients with CD in clinical remission (Crohn's Disease Activity Index ≤150) who underwent hybrid endoscopy between February 2021 and September 2023. These patients were compared with 53 contemporaneous patients who underwent small-bowel capsule endoscopy (SBCE) alone. Endoscopic remission (ER) was defined as Capsule Endoscopy Crohn's Disease Activity Index <3.5 and Simple Endoscopic Score for Crohn's Disease ≤2. Relapse rates were analyzed according to ER achievement and treatment modification using the Kaplan-Meier method. Results: Hybrid endoscopy resulted in a shorter small-bowel transit time (184 min vs. 243 min, Conclusions: This novel hybrid endoscopy approach permits a comprehensive assessment of CD activity using currently available technology. Hybrid endoscopy may be helpful in guiding treatment decisions, particularly treatment intensification in patients who have not achieved ER.

Indexed as

capsule endoscopyCrohn's diseaseendoscopic remissionileocolonoscopytreat‐to‐target

Identifiers

PMID41736957
PMCPMC12928045

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.