Evidence map›Paper›PMID 41736934›Full record

ArticlePhysics and imaging in radiation oncology2026

Dental metal artifacts in magnetic resonance-based synthetic computed tomography for brain radiotherapy: Impact on dose, patient setup, and geometric distortion.

Lisa Milan, Francesco Pupillo, Margherita Corsi, Matteo Coppotelli, Alessio Minoggio, Paula Sargenti, Stefano Moretto, Margherita Casiraghi, Maria Antonietta Piliero, Klaudia Krzekotowska and 5 more

Abstract read
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In one paragraph

Article in Physics and imaging in radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lisa MilanMedical Physics Division, Ente Ospedaliero Cantonale (EOC) - Imaging Institute of Southern Switzerland (IIMSI), Bellinzona, Switzerland.
Francesco PupilloMedical Physics Division, Ente Ospedaliero Cantonale (EOC) - Imaging Institute of Southern Switzerland (IIMSI), Bellinzona, Switzerland.
Margherita CorsiMedical Physics Division, Ente Ospedaliero Cantonale (EOC) - Imaging Institute of Southern Switzerland (IIMSI), Bellinzona, Switzerland.
Matteo CoppotelliMedical Physics Division, Ente Ospedaliero Cantonale (EOC) - Imaging Institute of Southern Switzerland (IIMSI), Bellinzona, Switzerland.
Alessio MinoggioMedical Physics Division, Ente Ospedaliero Cantonale (EOC) - Imaging Institute of Southern Switzerland (IIMSI), Bellinzona, Switzerland.
Paula SargentiRadiation Oncology, Ente Ospedaliero Cantonale (EOC) - Oncology Institute of Southern Switzerland (IOSI), Bellinzona, Switzerland.
Stefano MorettoRadiation Oncology, Ente Ospedaliero Cantonale (EOC) - Oncology Institute of Southern Switzerland (IOSI), Bellinzona, Switzerland.
Margherita CasiraghiMedical Physics Division, Ente Ospedaliero Cantonale (EOC) - Imaging Institute of Southern Switzerland (IIMSI), Bellinzona, Switzerland.
Maria Antonietta PilieroMedical Physics Division, Ente Ospedaliero Cantonale (EOC) - Imaging Institute of Southern Switzerland (IIMSI), Bellinzona, Switzerland.
Klaudia KrzekotowskaMedical Physics Division, Ente Ospedaliero Cantonale (EOC) - Imaging Institute of Southern Switzerland (IIMSI), Bellinzona, Switzerland.
Davide Giovanni BosettiRadiation Oncology, Ente Ospedaliero Cantonale (EOC) - Oncology Institute of Southern Switzerland (IOSI), Bellinzona, Switzerland.
Gianfranco PesceRadiation Oncology, Ente Ospedaliero Cantonale (EOC) - Oncology Institute of Southern Switzerland (IOSI), Bellinzona, Switzerland.
Francesco Mosè CastronovoRadiation Oncology, Ente Ospedaliero Cantonale (EOC) - Oncology Institute of Southern Switzerland (IOSI), Bellinzona, Switzerland.
Stefano PresillaMedical Physics Division, Ente Ospedaliero Cantonale (EOC) - Imaging Institute of Southern Switzerland (IIMSI), Bellinzona, Switzerland.
Thomas ZilliRadiation Oncology, Ente Ospedaliero Cantonale (EOC) - Oncology Institute of Southern Switzerland (IOSI), Bellinzona, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Magnetic resonance (MR)-based synthetic computed tomography (sCT) can improve target and organs-of-interest delineation in brain radiotherapy. However, metallic implants may cause anatomical inconsistencies, dose inaccuracies, and distortions. This study evaluates the impact of dental metal artifacts on MR-only workflow. Materials and methods: Ninety-six patients underwent MR and CT for radiotherapy planning; fifty-two with dental implants undergoing standard or stereotactic treatments were eligible. Dose-volume metrics (D Results: Median target dose differences remained within ±0.3%, with maximum of 3.7% for D Conclusions: Despite dental metal artifacts, sCT demonstrate dose accuracy comparable to standard CT. The results support clinical use of sCT in brain radiotherapy, with caution when artifacts alter the body near targets.

Indexed as

Brain MR-onlyDose comparisonGeometric distortionMetal dental implantSynthetic CT

Identifiers

PMID41736934
PMCPMC12926589

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