Evidence map›Paper›PMID 41736851›Full record

ArticleiScience2026

Shaping inter-brain plasticity: A feasibility study of enhancing inter-brain synchrony with dyadic neurofeedback.

Mario Francis, Andrey Markus, Fine Stuhr-Wulff, Simone Shamay-Tsoory

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mario FrancisDepartment of Psychology, University of Haifa, Mount Carmel, Haifa 3498838, Israel.
Andrey MarkusDepartment of Psychology, University of Haifa, Mount Carmel, Haifa 3498838, Israel.
Fine Stuhr-WulffDepartment of Psychology, University of Haifa, Mount Carmel, Haifa 3498838, Israel.
Simone Shamay-TsooryDepartment of Psychology, University of Haifa, Mount Carmel, Haifa 3498838, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inter-brain synchrony, the co-activation of brain regions between interacting individuals, is increasingly recognized as a key mechanism underlying social connectedness. This study examined whether dyadic neurofeedback training can enhance inter-brain synchrony in the inferior frontal gyrus and causally increase connectedness. We developed a real-time dyadic neurofeedback platform using functional near-infrared spectroscopy, where unacquainted dyads underwent three training sessions receiving either real neurofeedback or sham feedback. Although we initially anticipated a gradual increase across sessions, the neurofeedback group showed a significant enhancement in IFG inter-brain synchrony only in the third session, with effects extending to additional regions. These neural changes coincided with increased feelings of connectedness and shifts in intra-brain co-activation. While the precise strategies underlying dyadic regulation remain unclear, and additional sessions are needed to fully characterize the learning trajectory, the present findings provide preliminary evidence for the plasticity of inter-brain synchrony and its potential relevance for improving social outcomes.

Indexed as

cognitive neuroscienceneurosciencepsychology

Identifiers

PMID41736851
PMCPMC12927069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.