ArticleFrontiers in pediatrics2025
Postpartum TDF continuation in high HBV-DNA mothers: safety for breastfeeding and enhanced infant immunity.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- KASL clinical practice guidelines for management of chronic hepatitis B Endorsed by the East Asia Liver Alliance (EALA).Clinical and molecular hepatology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: High HBV-DNA load in pregnant women increases the risk of vertical transmission to infants. Tenofovir disoproxil fumarate (TDF) is an effective antiviral treatment, but its safety and efficacy in breastfeeding mothers with high HBV-DNA loads remain unclear. Methods: This retrospective cohort study included 210 high HBV-DNA load mothers, divided into a TDF-BF Group ( Results: The TDF-BF Group had significantly lower rates of vertical HBV transmission ( Conclusion: Postpartum continuation of TDF and breastfeeding is an effective and safe strategy for reducing vertical HBV transmission and promoting infant immunity in high HBV-DNA load mothers. Notably, Tenofovir was not detected in the infant plasma, supporting the safety of this approach.
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