ArticleEnvironmental epigenetics2026
Diazinon may increase the risk of acute lymphoblastic leukemia by inducing
Article in Environmental epigenetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and objective: Acute lymphoblastic leukemia (ALL) is the most frequent childhood malignancy, which is impacted by genetic, epigenetic, and environmental variables. Aberrant methylation of genes, such as O6-methylguanine-DNA-methyltransferase ( Methods: This case-control research was performed on 136 children with ALL and 136 healthy children as the control group. Demographic data were gathered using a questionnaire and blood sampling. Serum concentrations of diazinon were determined using gas chromatography (GC). DNA was extracted from nucleated cells, followed by bisulfite treatment and examination of Results: Diazinon levels were significantly increased in ALL patients compared to controls ( Conclusion: Exposure to diazinon might contribute to the development and progression of ALL by triggering aberrant methylation of the
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