Evidence map›Paper›PMID 41736755›Full record

ArticleCase reports in infectious diseases2026

Extraneurological Presentations of Tick-Borne Encephalitis Virus: A Rare Case of TBEV-Associated Myocarditis With Fever and Bicytopenia and a Systematic Literature Review.

Marco Seneghini, Fabiola Lugano, Micha T Maeder, Regine Garcia-Boy, Carol Strahm

Abstract read
In one paragraph

Article in Case reports in infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marco SeneghiniDepartement of Infectious Diseases and Hospital Hygiene, Cantonal Hospital of St. Gallen, St. Gallen, Switzerland, kssg.ch.ORCID https://orcid.org/0000-0002-3007-2641
Fabiola LuganoDepartment of Internal Medicine, Cantonal Hospital of St. Gallen, St. Gallen, Switzerland, kssg.ch.
Micha T MaederDepartment of Cardiology, Cantonal Hospital of St. Gallen, St. Gallen, Switzerland, kssg.ch.
Regine Garcia-BoyDivision of Human Microbiology, Center for Laboratory Medicine, St. Gallen, Switzerland.
Carol StrahmDepartement of Infectious Diseases and Hospital Hygiene, Cantonal Hospital of St. Gallen, St. Gallen, Switzerland, kssg.ch.ORCID https://orcid.org/0000-0002-1713-262X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Tick-borne encephalitis (TBE), a zoonotic disease caused by the tick-borne encephalitis virus (TBEV), usually manifests with a biphasic course with neurological involvement during its second phase. Extraneurological manifestations are rare but clinically relevant. Methods: We report a case of a 77-year-old patient with suspected acute myocarditis associated with central European TBEV infection and summarize the literature on extraneurological TBEV manifestations through a systematic review. Results: The case of a 77-year-old patient with suspected acute myocarditis associated with central European TBEV infection is reported and discussed. Literature analysis identified 23 publications reporting extraneurological TBEV manifestations, including (peri)myocarditis, myositis, hematological abnormalities, and elevated transaminases. Conclusion: TBEV infection can be complicated by myocarditis and should therefore be considered in the differential diagnosis in areas where TBEV is endemic in a patient with risk factors for tick bites. Vaccination remains crucial for preventing TBEV infections.

Indexed as

myocarditismyopericarditisTBETBEVtick-borne encephalitistick-borne encephalitis virusticks

Identifiers

PMID41736755
PMCPMC12927943

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.