ArticleERJ open research2026
Parental smoke exposure before age 15 years and offspring asthma trajectories from ages 7 to 53 years.
Article in ERJ open research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Associations of activities of daily living and their trajectories with the risk of diabetes-related lower-limb amputation: evidence from the HRS and ELSA longitudinal cohorts.Frontiers in endocrinology · 2026Article
- Echoes of smoke: unwinding multigenerational asthma risk through longitudinal cohorts.ERJ open research · 2026Article
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and objective: Paternal passive smoke exposure before 15 years of age was associated with offspring childhood asthma, but its association with asthma beyond childhood had not been investigated. We aimed to investigate such long-term association. Methods: Data were from 1078 father-offspring and 1537 mother-offspring pairs from the Tasmanian Longitudinal Health Study. Offspring (probands of the original cohort) completed asthma surveys at age 7, 13, 18, 30, 43, 50 and 53 years. Life-course asthma trajectories were developed using group-based trajectory modelling. Parents self-reported their own passive smoke exposure before 15 years of age. Multinomial logistic regressions assessed associations between parental passive smoke exposure and offspring asthma trajectories. Active parental smoking, offspring sex, childhood respiratory illnesses and subsequent active smoking were evaluated for mediations and interactions. Results: Paternal passive smoke exposure before 15 years of age was associated with an early-onset adult-remitting asthma trajectory (adjusted multinomial odds ratio (aMOR) 2.53, 95% CI 1.09-5.85) in offspring, but not persistent asthma trajectories. Maternal passive smoke exposure before 15 years of age was associated with an early-onset adult-remitting asthma trajectory in offspring who were also exposed to childhood passive smoke (aMOR 4.30, 95% CI 1.01-18.40; p-interaction=0.044). The observed associations were partly mediated through active parental smoking or offspring childhood respiratory illnesses (each <10%). Conclusions: This study identified a novel association between parental passive smoke exposure before 15 years of age and an early-onset adult-remitting asthma trajectory in offspring, which is related to subsequent COPD. These findings suggest that in parents inevitably exposed to passive smoke during childhood/puberty, asthma risk in future generations associated with such exposure may be lower if parents avoid smoking around children.
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