Evidence map›Paper›PMID 41736179›Full record

ArticlePhysiological reports2026

Ensuring safety of exercise training through non-invasive measurement of cardiac function: A pilot study in adults.

Takayuki Fujiwara, Eisuke Amiya, Masao Takahashi, Atsuko Nakayama, Yuto Konishi, Masanobu Taya, Kanako Hyodo, Naoko Takayama, Issei Komuro, Norihiko Takeda

Abstract read
In one paragraph

Article in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Takayuki FujiwaraDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.ORCID 0000-0002-8719-3997
Eisuke AmiyaDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.ORCID 0000-0003-2810-8040
Masao TakahashiDepartment of Cardiovascular Medicine, JR Tokyo General Hospital, Shibuya-ku, Tokyo, Japan.
Atsuko NakayamaDepartment of Cardiology, Sakakibara Heart Institute, Fuchu, Tokyo, Japan.
Yuto KonishiDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Masanobu TayaDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Kanako HyodoDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Naoko TakayamaDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Issei KomuroDepartment of Frontier Cardiovascular Science, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
Norihiko TakedaDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac rehabilitation (CR) improves exercise capacity, but frequent cardiopulmonary exercise testing (CPET) is impractical. The AESCULON mini enables non-invasive hemodynamic monitoring, though its role in CR remains unclear. Eleven patients (6 myocardial infarction, 3 angina pectoris, 2 dilated cardiomyopathy) undergoing outpatient CR at the University of Tokyo Hospital were studied. Hemodynamics were measured using the AESCULON mini before and after 20 min of aerobic exercise at the anaerobic threshold. CPET and brain natriuretic peptide (BNP) were assessed within 2 weeks. Stroke volume, cardiac output, and cardiac index tended to increase, and thoracic fluid content (TFC) decreased post-exercise. TFC before (r = 0.767, p = 0.006) and after (r = 0.711, p = 0.014) correlated with BNP. Changes in stroke volume and cardiac output correlated with peak VO

Indexed as

Cardiac RehabilitationExerciseExercise TherapyAgedCardiac OutputExercise TestExercise ToleranceFemaleHemodynamicsHumansMaleMiddle AgedNatriuretic Peptide, BrainOxygen ConsumptionPilot ProjectsStroke VolumeNatriuretic Peptide, Brainaerobic exercise trainingAESCULONbrain natriuretic peptidecardiopulmonary exercise testingexercise capacity

Identifiers

PMID41736179
PMCPMC12932308

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.