ArticleJournal of anesthesia, analgesia and critical care2026
Characterization of lung microbiota in pneumonia: a pilot study in ICU and non-ICU patients.
Article in Journal of anesthesia, analgesia and critical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The trial behind it
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Who cites it
2 citing papers in PubMed.
- Artificial Intelligence Models for Mortality and Outcome Prediction in Intensive Care Unit Sepsis: A Systematic Review.Journal of personalized medicine · 2026Review
- Electrical impedance tomography assessment of bronchoalveolar lavage-associated lung derecruitment and its related factors: a single-center retrospective study.Frontiers in physiology · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
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Abstract
objectiveTo identify potential differences in lung microbiota according to clinical severity, age, and gender in pneumonia patients compared to controls.
designPilot study.
settingSingle center (Azienda Ospedaliera Universitaria Dulbecco, Catanzaro, Italy). PATIENTS: Thirty-three individuals-11 ICU patients requiring invasive mechanical ventilation, 11 non-ICU patients, and 11 cadaver controls without lung disease.
interventionsBronchoalveolar lavage sample collection and analysis via microbiological cultures and metagenomic sequencing. MEASUREMENTS AND MAIN
resultsBacteroidota and Verrucomicrobiota phyla were more abundant in older (≥65 years) ICU and non-ICU patients versus controls. Massilia timonae showed a significantly lower relative abundance at the group level in cases compared to controls, potentially increasing infection susceptibility. Higher microbiota diversity was observed in older patients.
conclusionsAlterations in lung microbiota composition were observed in pneumonia patients, with differences that appeared more evident in older patients. Microbiota phenotyping may offer novel insights into pneumonia pathophysiology and pulmonary dysbiosis.
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Registered trials
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