Evidence map›Paper›PMID 41736039›Full record

ArticleBMC oral health2026

The interrelationship of TMJ morphology, craniofacial structure, and airway dimensions in patients with disc displacement.

Almustafa Osama, Hai Juan Zhang, Mazen Musa, Mahmoud Nasih, Cheng Dong Zheng, Yu Han Ren, Shuang Wang

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Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Almustafa OsamaKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, People's Republic of China.ORCID 0009-0009-0838-8701
Hai Juan ZhangKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, People's Republic of China.
Mazen MusaLaboratory Centre of Stomatology, College of Stomatology, Xi'an Jiaotong University, Xi'an, People's Republic of China.ORCID 0000-0002-4545-6314
Mahmoud NasihKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, People's Republic of China.
Cheng Dong ZhengKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, People's Republic of China.
Yu Han RenKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, People's Republic of China.
Shuang WangKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, People's Republic of China. wshuang@xjtu.edu.cn.

Funding

This work was supported by the Shaanxi program on key research and development projects; Shaanxi Provincial Clinical Research Centre for Dental Diseases. (2018SF-031);(2020YHJB10)
6 · The paper itself

Abstract

backgroundThis study aimed to comprehensively analyse the interrelationships between temporomandibular joint (TMJ) morphology, craniofacial skeletal patterns, and oropharyngeal airway dimensions in patients with TMJ disc displacement (TMJ DD). METHODOLOGY: Based on the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) and subsequent MRI confirmation, this retrospective study included 91 adult patients with TMD DD. These patients were then categorized into three groups.: Bilateral Normal disc position (BN, n = 36), Disc Displacement with Reduction (DDR, n = 25), and Disc Displacement without Reduction (DDWR, n = 30). All participants underwent cone-beam computed tomography (CBCT) and cephalometric analysis of craniofacial structure and three-dimensional assessment of TMJ morphology (including joint spaces, fossa dimensions, and condylar inclination) and oropharyngeal airway volume (OPV) and area (OPA). Statistical analyses included one-way ANOVA/Kruskal–Wallis tests for group comparisons, Spearman's correlation to assess bivariate relationships, and multiple linear regression (MLR) to identify independent predictors of airway dimensions while controlling for confounders.

resultsSignificant differences were observed in craniofacial, TMJ characteristics, and oropharyngeal airway dimensions among the groups. The DDWR group exhibited a retrognathic and hyperdivergent skeletal pattern (larger ANB, smaller SNB, higher FMA; p < 0.05). The DDR group demonstrated a significantly steeper anterior condylar inclination and a more posteriorly positioned condyle. Crucially, oropharyngeal dimensions were significantly smaller in the DDR group compared to the BN group (OPV: 7688.56 ± 1770.14 mm3 vs. 10,562.47 ± 4185.89 mm3, p = 0.029; OPA: 410.76 ± 77.65 mm2 vs. 513.44 ± 145.21 mm2, p = 0.018). Correlation and MLR analyses revealed that a constricted airway was associated with mandibular retrognathism, specific TMJ features, and reduced vertical facial dimensions. Notably, glenoid fossa height was a significant positive predictor for both OPV and OPA.

conclusionsTMJ DD is associated with specific craniofacial patterns and reduced oropharyngeal airway dimensions. These findings underscore a significant association within the TMJ-craniofacial-airway complex, advocating for an integrated clinical approach in diagnosing and treating temporomandibular disorders and airway compromise.

Indexed as

Joint DislocationsOropharynxTemporomandibular Joint DiscTemporomandibular Joint DisordersAdolescentAdultCephalometryCone-Beam Computed TomographyFemaleHumansImaging, Three-DimensionalMagnetic Resonance ImagingMaleMandibular CondyleMiddle AgedRetrospective StudiesAirway VolumeCone beam computed tomographyCraniofacial morphologyDisc displacementMagnetic resonance imagingTemporomandibular disorders

Identifiers

PMID41736039
PMCPMC13156870

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.