Evidence map›Paper›PMID 41735704›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2026

Anxiolytic-like effects of p-coumaric acid via GABAergic interaction pathways: an in vivo and in silico study.

Madhu Sah, Balaram Das, Ramesh Kumar Mandal, Raihan Chowdhury, Mohammad Y Alshahrani, Muhammad Ali Khan, Anik Kumar Saha, U Ching Aoung Chak, Sadia Akhter, Md Fazla Alahi Nikson and 5 more

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Article in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Madhu SahDepartment of Pharmacy, Gopalganj Science and Technology University, Gopalganj, 8105, Bangladesh.
Balaram DasDepartment of Pharmacy, Gopalganj Science and Technology University, Gopalganj, 8105, Bangladesh.
Ramesh Kumar MandalDepartment of Pharmacy, Gopalganj Science and Technology University, Gopalganj, 8105, Bangladesh.
Raihan ChowdhuryDepartment of Pharmacy, Gopalganj Science and Technology University, Gopalganj, 8105, Bangladesh.
Mohammad Y AlshahraniCentral Labs, King Khalid University, P.O. Box 61413, Abha, 9088, Saudi Arabia.
Muhammad Ali KhanDepartment of Pharmacy, Gopalganj Science and Technology University, Gopalganj, 8105, Bangladesh. rumel.ph@gmail.com.
Anik Kumar SahaDepartment of Pharmacy, Gopalganj Science and Technology University, Gopalganj, 8105, Bangladesh.
U Ching Aoung ChakDepartment of Pharmacy, Gopalganj Science and Technology University, Gopalganj, 8105, Bangladesh.
Sadia AkhterDepartment of Pharmacy, Gopalganj Science and Technology University, Gopalganj, 8105, Bangladesh.
Md Fazla Alahi NiksonDepartment of Pharmacy, Gopalganj Science and Technology University, Gopalganj, 8105, Bangladesh.
Shama MohantaDepartment of Pharmacy, Gopalganj Science and Technology University, Gopalganj, 8105, Bangladesh.
H M Shadid Hossain SnigdhaDepartment of Pharmacy, Gopalganj Science and Technology University, Gopalganj, 8105, Bangladesh. shadidhossain89@gmail.com.
Muhammad Torequl IslamDepartment of Pharmacy, Gopalganj Science and Technology University, Gopalganj, 8105, Bangladesh.
Anike ChakrabartyDepartment of Biotechnology, Faculty of Engineering and science, University of Greenwich, Medway, Central Avenue, Kent, UK.
Md Sakib Al HasanDepartment of Pharmacy, Gopalganj Science and Technology University, Gopalganj, 8105, Bangladesh. mdsakibalhasan192412@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

p-Coumaric acid (PCA) is a naturally occurring phenolic compound widely distributed in plants, known for its antioxidant, anti-inflammatory, and antimicrobial properties. The present study's objective was to perform behavioral tests and in silico molecular docking with GABA

Indexed as

Anti-Anxiety AgentsAnxietyCoumaric AcidsPropionatesReceptors, GABA-AAnimalsBehavior, AnimalDiazepamDose-Response Relationship, DrugFlumazenilMaleMiceMolecular Docking SimulationAnti-Anxiety AgentsCoumaric AcidsDiazepamFlumazenilp-coumaric acidPropionatesReceptors, GABA-AAnxietyAnxiolytic activityDiazepamFlumazenilGABAergic systemP-Coumaric acid

Identifiers

PMID41735704

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.