Evidence map›Paper›PMID 41735391›Full record

ArticleScientific reports2026

Genome-wide association study of Mycoplasma anserisalpingitidis strains for antibiotic susceptibility.

Áron B Kovács, Enikő Wehmann, Katinka Bekő, Dénes Grózner, Krisztina Bali, Zsuzsa Kreizinger, Anna Sawicka, Krisztián Bányai, Miklós Gyuranecz

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Áron B KovácsHUN-REN Veterinary Medical Research Institute, Hungária Krt. 21, Budapest, 1143, Hungary.
Enikő WehmannHUN-REN Veterinary Medical Research Institute, Hungária Krt. 21, Budapest, 1143, Hungary.
Katinka BekőHUN-REN Veterinary Medical Research Institute, Hungária Krt. 21, Budapest, 1143, Hungary.
Dénes GróznerHUN-REN Veterinary Medical Research Institute, Hungária Krt. 21, Budapest, 1143, Hungary.
Krisztina BaliHUN-REN Veterinary Medical Research Institute, Hungária Krt. 21, Budapest, 1143, Hungary.
Zsuzsa KreizingerHUN-REN Veterinary Medical Research Institute, Hungária Krt. 21, Budapest, 1143, Hungary.
Anna SawickaDepartment of Poultry Diseases, National Veterinary Research Institute, Aleja Partyzantow 57, 24-100, Pulawy, Poland.
Krisztián BányaiHUN-REN Veterinary Medical Research Institute, Hungária Krt. 21, Budapest, 1143, Hungary.
Miklós GyuraneczHUN-REN Veterinary Medical Research Institute, Hungária Krt. 21, Budapest, 1143, Hungary. m.gyuranecz@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycoplasma anserisalpingitidis is a facultative pathogenic bacterium affecting waterfowl, predominantly geese and sporadically ducks. Understanding the molecular basis of antimicrobial resistance mechanisms is crucial in the preservation of antibiotic efficiency. This study aimed to elucidate the genetic background of antibiotic susceptibility profiles of 110 M. anserisalpingitidis strains against nine antimicrobial agents. Significant associations between k-mers and five (tylvalosin, tilmicosin, enrofloxacin, lincomycin, spectinomycin) of the nine antimicrobial agents were identified by pyseer. Significant associations were found in multiple coding sequences that encode various members of efflux pumps, epigenetic regulation and topoisomerases among many other groups of functions. Certain k-mers associated with genes found putative prophage-like sequences suggest potential horizontal gene transfer events that could facilitate the acquisition of novel resistance mechanisms. Based on our findings, the genetic background of antimicrobial resistance of M. anserisalpingitidis is composed of multiple factors. Our results not only correlated with the majority of known antibiotic resistance mechanisms (e.g. drug target modification, efflux pumps, methyltransferases) but also showed potentially novel genes that could play a significant role in antimicrobial resistance. The results may serve to expedite the diagnosis of M. anserisalpingitidis antibiotic susceptibility profiles and support the fight against the spreading of resistance.

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialGenome-Wide Association StudyAnimalsGenome, BacterialMicrobial Sensitivity TestsAnti-Bacterial AgentsAminocyclitolAntibiotic susceptibilityFluoroquinoloneLincosamideMacrolidePleuromutilinTetracylineWaterfowlWhole genome analysis

Identifiers

PMID41735391
PMCPMC13031706

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.