Evidence map›Paper›PMID 41735346›Full record

ArticleNature communications2026

Stem-like memory-T maintenance and differentiation into tissue-resident T cells sustain chronic graft-versus-host disease in mice.

Xiaohui Kong, Bixin Wang, Xiwei Wu, Hyejin Cho, Weijia Fu, Qinjian Li, Rong Zhang, Ubaydah Nasri, Moqian Zheng, Alyssa Wu and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Xiaohui Kong *Department of Immunology and Theranostics, Arthur Riggs Institute of Diabetes and Metabolism Research, The Beckman Research Institute of City of Hope, Duarte, CA, USA.
Bixin Wang *Department of Immunology and Theranostics, Arthur Riggs Institute of Diabetes and Metabolism Research, The Beckman Research Institute of City of Hope, Duarte, CA, USA.ORCID http://orcid.org/0009-0000-9613-2734
Xiwei WuDepartment of Integrative Genomics Core, The Beckman Research Institute of City of Hope, Duarte, CA, USA.
Hyejin ChoDepartment of Integrative Genomics Core, The Beckman Research Institute of City of Hope, Duarte, CA, USA.ORCID http://orcid.org/0000-0002-9954-8118
Weijia FuDepartment of Immunology and Theranostics, Arthur Riggs Institute of Diabetes and Metabolism Research, The Beckman Research Institute of City of Hope, Duarte, CA, USA.ORCID http://orcid.org/0000-0001-7235-5853
Qinjian LiDepartment of Immunology and Theranostics, Arthur Riggs Institute of Diabetes and Metabolism Research, The Beckman Research Institute of City of Hope, Duarte, CA, USA.ORCID http://orcid.org/0000-0001-8998-8446
Rong ZhangDepartment of Immunology and Theranostics, Arthur Riggs Institute of Diabetes and Metabolism Research, The Beckman Research Institute of City of Hope, Duarte, CA, USA.
Ubaydah NasriDepartment of Immunology and Theranostics, Arthur Riggs Institute of Diabetes and Metabolism Research, The Beckman Research Institute of City of Hope, Duarte, CA, USA.
Moqian ZhengDepartment of Immunology and Theranostics, Arthur Riggs Institute of Diabetes and Metabolism Research, The Beckman Research Institute of City of Hope, Duarte, CA, USA.
Alyssa WuDepartment of Immunology and Theranostics, Arthur Riggs Institute of Diabetes and Metabolism Research, The Beckman Research Institute of City of Hope, Duarte, CA, USA.
Hanjun QinDepartment of Integrative Genomics Core, The Beckman Research Institute of City of Hope, Duarte, CA, USA.
Joey H LiDepartment of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Raju PillaiDepartment of Pathology, City of Hope National Comprehensive Cancer Center, Duarte, CA, USA.
Timothy E O'SullivanDepartment of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-1435-8188
Ryotaro NakamuraHematologic Malignancies and Stem Cell Transplantation Institute, City of Hope National Medical Center, Duarte, CA, USA.
Paul J MartinFred Hutchinson Cancer Center, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-9051-1215
Yuanzhong ChenFujian Medical University Center of Translational Hematology, Fujian Medical University Union Hospital, Fuzhou, Fujian, China. chenyz@fjmu.edu.cn.ORCID http://orcid.org/0000-0002-9411-1427
Defu ZengDepartment of Immunology and Theranostics, Arthur Riggs Institute of Diabetes and Metabolism Research, The Beckman Research Institute of City of Hope, Duarte, CA, USA. dzeng@coh.org.ORCID http://orcid.org/0000-0001-9585-1411

Funding

Pathogenesis, prevention and treatment of corticosteroid-resistant gut GVHDR01HL162847 · NHLBI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI Robert Jenq · 2023 to 2026
$3.4M
Role of autoreactivity in pathogenesis of chronic graft versus host diseaseR01HL170099 · NHLBI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI Robert Jenq · 2024 to 2026
$2.6M
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL162847U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL170099
6 · The paper itself

Abstract

Pathogenic CD4

Indexed as

CD4-Positive T-LymphocytesCell DifferentiationGraft vs Host DiseaseImmunologic MemoryMemory T CellsAdoptive TransferAnimalsAntigens, CDAntigens, Differentiation, T-LymphocyteBasic Helix-Loop-Helix ProteinsChronic DiseaseFemaleHepatocyte Nuclear Factor 1-alphaLectins, C-TypeMiceMice, Inbred C57BLAntigens, CDAntigens, Differentiation, T-LymphocyteBasic Helix-Loop-Helix ProteinsBcl6 protein, mouseHepatocyte Nuclear Factor 1-alphaHnf1a protein, mouseLectins, C-TypeProto-Oncogene Proteins c-bcl-6

Identifiers

PMID41735346
PMCPMC13043700

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.