Evidence map›Paper›PMID 41735303›Full record

ArticleNature communications2026

Male obesity causes adipose mitochondrial dysfunction in F

Chien Huang, Joo-Hyun Park, Ali Altıntaş, Natasa Stanic, Kristine Kyle de Leon, Signe Isacson, Panagiotis Kalogeropoulos, Hande Topel, Tobias Madsen, Sebastian Zanner and 26 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Chien Huang *Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Joo-Hyun Park *Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Ali AltıntaşNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-8932-0160
Natasa StanicDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Kristine Kyle de LeonDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.ORCID http://orcid.org/0009-0009-3507-410X
Signe IsacsonDivision of Cell and Neurobiology, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.ORCID http://orcid.org/0000-0002-7590-8326
Panagiotis KalogeropoulosScience for Life Laboratory, Department of Molecular Biosciences, The Wenner-Gren-Institute, Stockholm University, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-6717-5011
Hande TopelDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.ORCID http://orcid.org/0000-0001-5743-4019
Tobias MadsenDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.ORCID http://orcid.org/0009-0008-5293-3415
Sebastian ZannerDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Phillip Mm RuppertDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Rocio ValdebenitoDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Jesper HavelundDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.ORCID http://orcid.org/0000-0002-9797-5431
Bjørk Ditlev Marcher LarsenDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Yen-Ting ChienLaboratory of Animal Physiology, Department of Animal Science and Technology, National Taiwan University, Taipei, Taiwan.
Wen-Chi HuangLaboratory of Animal Physiology, Department of Animal Science and Technology, National Taiwan University, Taipei, Taiwan.
Yovita Permata BudiGraduate Institute of Molecular and Comparative Pathobiology, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.ORCID http://orcid.org/0000-0002-9901-6752
Yi-Fan JiangGraduate Institute of Molecular and Comparative Pathobiology, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.ORCID http://orcid.org/0000-0002-1692-4385
Andréa Livia RochaClayton Foundation Laboratories for Peptide Biology, Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-9044-980X
Niedson Correia Lima-JuniorDepartment of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, SP, Brazil.
Karolina SzczepanowskaCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases & Center for Molecular Medicine, University of Cologne, Cologne, Germany.
Jan-Wilm LackmannCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases & Center for Molecular Medicine, University of Cologne, Cologne, Germany.ORCID http://orcid.org/0000-0001-8182-8034
Aleksandra TrifunovicCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases & Center for Molecular Medicine, University of Cologne, Cologne, Germany.ORCID http://orcid.org/0000-0002-5472-3517
Eva Kildall HejbølWinsløw Unit for Anatomy, Histology and Plastination, Department of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Sönke DetlefsenDepartment of Pathology, Odense University Hospital, Odense, Denmark.ORCID http://orcid.org/0000-0002-9466-2333
Ida Engberg JepsenThe Fertility Clinic, Department of Obstetrics and Gynaecology, Zealand University Hospital, Koege, Denmark.ORCID http://orcid.org/0000-0002-4632-4292
Stefanie Hansborg KolstrupBiomedical Laboratory, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Ricardo Laguna-BarrazaCore Facility for Transgenic Mice, Department of Experimental Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Javier Martin-GonzalezCore Facility for Transgenic Mice, Department of Experimental Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-7075-6028
Konstantin KhodosevichBiotech Research & Innovation Centre, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-7232-5558
Nils J FærgemanDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.ORCID http://orcid.org/0000-0002-9281-5287
Marcelo A MoriDepartment of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-7112-5263
Marc R FriedländerScience for Life Laboratory, Department of Molecular Biosciences, The Wenner-Gren-Institute, Stockholm University, Stockholm, Sweden.
Anita ÖstDivision of Cell and Neurobiology, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.ORCID http://orcid.org/0000-0003-0547-1904
Romain BarrèsNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-0158-519X
Jan-Wilhelm KornfeldDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark. janwilhelmkornfeld@bmb.sdu.dk.ORCID http://orcid.org/0000-0002-6802-4442

Funding

Novo Nordisk Fonden (Novo Nordisk Foundation) 33444
6 · The paper itself

Abstract

Male obesity negative affects gametic function and offspring metabolism. We here describe that (F

Indexed as

Adipose TissueDEAD-box RNA HelicasesMicroRNAsMitochondriaObesityRibonuclease IIIAnimalsFemaleHumansMaleMiceMice, Inbred C57BLSpermatozoaWeight LossDEAD-box RNA HelicasesDicer1 protein, mouseMicroRNAsmirnlet7 microRNA, mouseRibonuclease III

Identifiers

PMID41735303
PMCPMC13043754

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.