ReviewCurrent medicinal chemistry2026
Curcumin and Curcuminoids: Biological Activities and Clinical Studies.
Review in Current medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The dynamic trajectory of circulating exosome components in high-fat diet-induced metabolic-associated steatotic liver disease and its modulation by curcuminoids.Frontiers in endocrinology · 2026Article
- Modulatory effects of traditional Chinese medicine and derived active metabolites on autoimmune-inflammatory signaling pathways in multiple sclerosis: a narrative review.Frontiers in pharmacology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCurcuma longa L. (turmeric) is an herbaceous perennial plant belonging to the Zingiberaceae (ginger) family. A lipophilic substance called "curcumin", a spice widely used in different cuisines, is extracted from the rhizome of this plant through drying and milling. This spice confers a flavor and the typical yellow-orange color to food, and has always attracted the attention of the scientific community due to the presence of polyphenols with remarkable biological activities, including curcuminoids, which consist of curcumin, demethoxycurcumin, and bisdemethoxycurcumin. Curcumin and curcuminoids exhibit different biological activities in vitro; however, their effectiveness in vivo is limited. Consequently, numerous formulations have been developed to enhance bioavailability and demonstrate promising effects for the treatment of various illnesses.
methodsFor this narrative review, the PubMed, Web of Science, Scopus, and Google Scholar databases were searched using the following key terms in titles and abstracts: nanocurcumin, curcumin nanoparticle, curcumin nanoformulations, intervention studies, controlled trials, randomized controlled trials, and clinical trials.
resultsThis review describes the effects of curcumin and its derivatives as antimicrobial, anti-inflammatory, and antioxidant molecules, and their involvement in cancer, with a focus on epigenetic, chronic degenerative, and autoimmune diseases. Moreover, clinical trials using certain curcumin-based nanoformulations have also been reported. DISCUSSION: The important biological effects of curcumin and curcuminoids, together with their nanoformulations, are discussed in this review.
conclusionAll the beneficial properties of curcumin may complement conventional drug therapies and enhance their effectiveness in disorders associated with chronic inflammation and oxidative stress.
Indexed as
Identifiers
41735207What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.