Evidence map›Paper›PMID 41735184›Full record

ArticleInternational journal of cosmetic science2026

A novel all-in-one dynamic wrinkle evaluation system: Development, validation and application in cosmetic industries.

Xingzuo Liu, Juanjuan Chen, Chengda Ye, Andrew Steel, Yidong Tu, Frederic Flament, Jing Li

Abstract readValidation Study
In one paragraph

Article in International journal of cosmetic science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xingzuo LiuL'Oréal Research and Innovation, Shanghai, China.
Juanjuan ChenL'Oréal Research and Innovation, Shanghai, China.
Chengda YeL'Oréal Research and Innovation, Shanghai, China.
Andrew SteelL'Oréal Research and Innovation, Shanghai, China.
Yidong TuL'Oréal Research and Innovation, Shanghai, China.
Frederic FlamentL'Oréal Research and Innovation, Paris, France.
Jing LiL'Oréal Research and Innovation, Shanghai, China.ORCID https://orcid.org/0009-0001-9775-5965

Funding

L'Oréal Research and Innovation
6 · The paper itself

Abstract

objectiveThis study aimed to develop and validate a novel, integrated dynamic wrinkle assessment system based on standardized, real-time and multi-angle facial images and video recordings, and to explore its potential application in evaluating the anti-wrinkle efficacy of skincare products.

methodsA standardized protocol was developed for a novel system integrating a high-precision positioning apparatus with synchronized, multi-angle high-speed cameras to capture facial expressions from a neutral to a maximal state. To ensure longitudinal consistency, a novel algorithm was used to select analysis frames based on angular congruence. The system's reproducibility and accuracy were validated by expert dermatologists using the intraclass correlation coefficient (ICC). The system's feasibility and effectiveness were assessed in an 8-week anti-wrinkle cream efficacy trial.

resultsThe integrated dynamic wrinkle evaluation system demonstrated high inter-rater reliability (ICC >0.70) across 35 Chinese women, with ICC values exceeding 0.900 for key facial areas. In an anti-aging efficacy trial (n = 42), the system successfully detected and quantified significant improvements (p < 0.05) in both static and dynamic wrinkles following product use.

conclusionThis study successfully developed and validated an all-in-one dynamic wrinkle photo grading evaluation system for personalized assessment of treatment outcomes following topical application of cosmetic products. The high accuracy of the clinician evaluations offers a new approach for assessing the effects of anti-aging skincare and cosmetic products, surpassing traditional static assessment methods.

Indexed as

CosmeticsSkin AgingAdultFemaleHumansMiddle AgedReproducibility of ResultsCosmeticscomputer modellingdermatologydynamic wrinklesformulationstatic wrinklesstatistics

Identifiers

PMID41735184
PMCPMC13636164

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.