ArticleYonsei medical journal2026
The Clinical Impact of Corticosteroid Supplementation in Febrile Patients with Adrenal Insufficiency.
Article in Yonsei medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
purposeCorticosteroids are frequently administered to febrile patients with adrenal insufficiency to improve their clinical course. However, the effect of corticosteroid supplementation in these patients remains uncertain. This study evaluates the effect of corticosteroid supplementation on the clinical outcomes of these patients. MATERIALS AND
methodsThis retrospective study was conducted at a tertiary hospital with 855 beds in South Korea. Adult inpatients (≥19 years) who had undergone an adrenocorticotropic hormone (ACTH) stimulation test to identify the cause of fever (≥37.8℃) between 1 July 2019, and 30 June 2022 were included. The included patients were categorized based on corticosteroid supplementation until discharge. Clinical outcomes between the two groups were compared, and logistic regression analysis identified factors associated with prolonged hospitalization.
resultsOf 216 patients, 74 (34.3%) received systemic corticosteroid supplementation. The median length of hospital stay after the ACTH stimulation test did not differ significantly between the two groups (7 days vs. 11.5 days,
conclusionAdministering corticosteroids to febrile patients with adrenal insufficiency did not show a significant impact on clinical outcomes and should be considered only after careful assessment in the clinical context.
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