Trial reportBehaviour research and therapy2026
Patient outcomes and session dose in a randomized controlled trial of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction: Influential factors and methodological considerations.
Trial report in Behaviour research and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveRandomized controlled trials (RCTs) assessing the implementation of evidence-based psychological treatments (EBPTs) into clinical practice may involve variations that are not always systematically investigated. This study aimed to investigate the impact of such variations in the context of an effectiveness-implementation hybrid trial - specifically, the relationship between trial outcomes and number of treatment sessions, dropout, and differences in assessment timing.
methodAdults (N = 539) with sleep and circadian problems were randomized to the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TSC; Adapted or Standard version) or usual care followed by delayed treatment (UC-DT).
resultsParticipants who completed the recommended number of TSC sessions showed larger effect sizes and more significant improvements relative to UC-DT, when compared to participants who received a partial session dose. Notably, a substantial number of participants who dropped out of treatment showed a meaningful clinical change by mid-treatment (20%), though this number did not differ significantly from the number of patients who received the full dose of treatment. Larger treatment effects were observed when assessments were completed within 3 months of their planned date. Kaplan-Meier Survival Analyses indicated that the dose to optimize the primary outcome of sleep disturbance at post-treatment was eight sessions for Standard TSC and six sessions for Adapted TSC.
conclusionsThis study underscores the impact of methodological variations on treatment outcomes in the implementation of TSC into clinical practice. Furthermore, our findings establish specific session thresholds for Standard and Adapted TSC to optimize clinical outcomes.
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