Evidence map›Paper›PMID 41734373›Full record

Observational studyJournal of medical Internet research2026

Rising to the Challenge of Early Screening in Primary Health Care Through the Web Italian Network for Autism Spectrum Disorder (Win4ASD) in the Pediatric Population: Retrospective Observational Study.

Noemi Buo, Eleonora Rosi, Silvia Busti Ceccarelli, Mariarosa Ferrario, Valerio Maiorca, Erika Morandi, Nicole Viganó, Ivan Limosani, Laura Falcone, Massimo Molteni and 1 more

Erratum issuedAbstract readObservational Study
In one paragraph

Observational study in Journal of medical Internet research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Noemi Buo *Child Psychopathology Unit-Smart Lab, Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Eugenio Medea, Bosisio Parini, Lecco, Italy.ORCID 0009-0002-5758-2112
Eleonora Rosi *Child Psychopathology Unit-Smart Lab, Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Eugenio Medea, Bosisio Parini, Lecco, Italy.ORCID 0000-0002-7080-8916
Silvia Busti CeccarelliChild Psychopathology Unit-Smart Lab, Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Eugenio Medea, Bosisio Parini, Lecco, Italy.ORCID 0000-0001-6809-4523
Mariarosa FerrarioAzienda Socio Sanitaria Territoriale della Valle Olona - Dipartimento di salute mentale e delle dipendenze, Gallarate, Varese, Italy.ORCID 0009-0006-3411-3478
Valerio MaiorcaAzienda Socio Sanitaria Territoriale della Valle Olona - Dipartimento di salute mentale e delle dipendenze, Gallarate, Varese, Italy.ORCID 0009-0004-1932-4264
Erika MorandiAzienda Socio Sanitaria Territoriale della Valle Olona - Dipartimento di salute mentale e delle dipendenze, Gallarate, Varese, Italy.ORCID 0009-0001-7022-1576
Nicole ViganóChild Psychopathology Unit-Smart Lab, Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Eugenio Medea, Bosisio Parini, Lecco, Italy.ORCID 0000-0001-9151-4151
Ivan LimosaniDirezione Generale Welfare, Lombardy Region, Milan, Italy.ORCID 0009-0006-3251-2045
Laura FalconeDirezione Generale Welfare, Lombardy Region, Milan, Italy.ORCID 0009-0003-1152-8150
Massimo MolteniChild Psychopathology Unit-Smart Lab, Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Eugenio Medea, Bosisio Parini, Lecco, Italy.ORCID 0000-0001-6268-5883
Paola ColomboChild Psychopathology Unit-Smart Lab, Scientific Institute, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Eugenio Medea, Bosisio Parini, Lecco, Italy.ORCID 0000-0003-4687-5913

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly identification of autism spectrum disorder (ASD) and neurodevelopmental disorders is a key element in the ability to intervene early and improve children's outcomes. The American Academy of Pediatrics recommends routine autism screening for children aged 18 to 24 months. Telemedicine (health care services delivered remotely using digital technologies) is a valuable tool in supporting this objective. As highlighted in the literature, telemedicine increases the availability of treatment, reduces diagnostic waiting times, and supports the monitoring of neurodevelopmental disorders. The Web Italian Network for Autism Spectrum Disorder (Win4ASD) platform is a telemedicine-based screening tool designed to detect ASD early within the pediatric health care system in Italy.

objectiveThis study investigated the integration of the Win4ASD platform into the Italian National Health Service, providing a detailed account of its operational features and use patterns among family pediatricians. It further examined the platform's contribution to reinforcing preventive health care strategies and enhancing coordination across child health services. Finally, through a retrospective observational analysis, this study evaluated the clinical effectiveness of Win4ASD in facilitating the early detection of ASD and improving screening outcomes.

methodsThe Win4ASD platform, which is active in the Lombardy region, helps family pediatricians screen toddlers for autism at an early age (18-24 months) using the Checklist for Autism in Toddlers. Furthermore, children identified as at risk are referred for further diagnostic evaluation to the local specialized autism unit-a mental health specialist team comprising child neuropsychiatrists, psychologists, and developmental therapists. This platform, which created an integrated network for early identification of autism, ensures rapid access to diagnostic and therapeutic services. This study analyzed data collected from the platform between January 2022 and September 2024 to assess family pediatricians' commitment and effectiveness in identifying children at risk of autism using descriptive analyses performed in SPSS.

resultsThe first key finding was the commitment of family pediatricians from the Regional Public Health Services in Lombardy to use the platform. In total, 72.5% (909/1253) of all family pediatricians working for the Regional Public Health Services actively used the platform. The platform enabled the screening of 58,419 infants from the general population in Lombardy, of whom 596 (1%) were identified as "at risk" and referred for fast-track diagnostic evaluation, which is consistent with global prevalence rates. In addition, diagnostic outcomes from a subsample are presented, showing the effectiveness of the platform in facilitating the early diagnosis of neurodevelopmental disorders.

conclusionsEarly identification of risk and timely intervention can prevent the progressive development of behavioral atypicalities, have a significant impact on the quality of life of the child and their family, and allow for a reduction in health care costs and a consequent improvement in the organization of the health care system.

Indexed as

Autism Spectrum DisorderInternetMass ScreeningPrimary Health CareChild, PreschoolEarly DiagnosisHumansInfantItalyRetrospective StudiesTelemedicineautism spectrum disorderCHATearly detectionhealth care policyonline screeningprimary carescreening Checklist for Autism in Toddlerssurveillance systemtele–mental health

Identifiers

PMID41734373
PMCPMC12976592

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.