Observational studyEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2026
Descending Thoracic Aortic Diameter Is a Predictor of Poor Outcome After Endovascular Aortic Repair.
Observational study in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01658787 ('GREAT' Global Registry for Endovascular Aortic Treatment - Outcomes Evaluation), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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'GREAT' Global Registry for Endovascular Aortic Treatment - Outcomes Evaluation
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8 authors.
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Abstract
objectivesTo evaluate the results of thoracic endovascular aortic repair (TEVAR) in large (diameter ≥7 cm) aneurysms of the descending thoracic aorta.
methodsThis cohort has been extrapolated from the prospective, observational (on-label and off-label), worldwide multicentre Global Registry for Endovascular Aortic Treatment (GREAT) (NCT01658787). Patients were divided into 2 groups based on the baseline aortic diameter: standard aneurysms (<7 cm) and larger aneurysms (≥7 cm). Primary outcomes were overall survival and freedom from TEVAR-related reintervention. Secondary outcomes were freedom from aortic-related mortality (ARM), as well as from type 1 endoleaks, and cumulative risk of TEVAR-related infection and/or aorto-bronchial/oesophageal fistulization.
resultsWe analysed 613 (80.4%) patients with standard aneurysms and 149 (19.6%) with larger aneurysms. Demographic data and comorbidities were not different between the groups. At the 4- to 6-year window, 496 (65.1%) patients remained under follow-up (standard, n = 409 [66.7%] vs large, n = 87 [58.4%]; odds ratio [OR]: 1.4, P = .056). Large aneurysm diameter was independently associated with higher hazards for all-cause mortality (hazard ratio [HR]: 1.6, 95% CI, 1.19-2.20; P < .001), TEVAR-related reintervention (HR: 2.4, 95% CI, 1.52-3.65; P < .001), risk of ARM (HR: 2.2, 95% CI, 1.03-4.75; P = .026), cumulative risk of TEVAR-related infection/fistulization, and type 1 endoleaks (HR: 3.3, 95% CI, 1.89-5.65; P < .001).
conclusionsPreoperative descending thoracic aortic diameter seems to be an important determinant of outcomes after TEVAR, where patients presenting with aortic diameter ≤ 7 cm showed more favourable long-term outcomes.
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