Evidence map›Paper›PMID 41733873›Full record

ArticleEmergency radiology2026

Diagnosis of acute appendicitis at a pediatric emergency department within a general hospital.

Cade A Johnson, Catherine M Pivalizza, Hei Kit Chan, Hannah Smith, Megan K Long, Robert Lapus, KuoJen Tsao, Susan John, Irma T Ugalde

Abstract read
In one paragraph

Article in Emergency radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cade A Johnson *Department of Emergency Medicine, McGovern Medical School at The University of Texas Health Science Center, Houston, TX, USA.
Catherine M Pivalizza *McGovern Medical School at The University of Texas Health Science Center, Houston, TX, USA. catherine.pivalizza@uth.tmc.edu.ORCID http://orcid.org/0009-0002-9540-8633
Hei Kit ChanUniversity of Texas Health Science Center at Houston School of Public Health, Houston, TX, USA.
Hannah SmithDepartment of Pediatric Emergency Medicine, Tristar Emergency Medicine Residency Training Program, Nashville, TN, USA.
Megan K LongMemorial Hermann Hospital, Sugarland, TX, USA.
Robert LapusDepartment of Emergency Medicine, McGovern Medical School at The University of Texas Health Science Center, Houston, TX, USA.
KuoJen TsaoDepartment of Pediatric Surgery and Neurosurgery, McGovern Medical School at The University of Texas Health Science Center, Houston, TX, USA.
Susan JohnDepartment of Diagnostic and Interventional Radiology, McGovern Medical School at The University of Texas Health Science Center, Houston, TX, USA.
Irma T UgaldeDepartment of Pediatrics, Section of Emergency Medicine, University of Chicago Pritzker School of Medicine, Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeUltrasound (US) has evolved as the principal imaging modality in the evaluation of pediatric appendicitis due to inherent advantages but may vary in performance based on setting. Rapid focused Magnetic Resonance Imaging (rapid MRI) is a feasible alternative, but emergency department (ED) length of stay (LOS) may be impacted. We wished to determine the performance and LOS of US and rapid MRI in a pediatric ED within a general hospital in the evaluation of appendicitis.

methodsWe conducted a retrospective diagnostic accuracy study of patients < 18 years of age with abdominal pain receiving imaging for evaluation of appendicitis (US or rapid MRI). We report descriptive statistics on demographics and clinical characteristics of the study population. We conducted a sensitivity analysis by the different imaging type and combinations performed.

resultsSensitivity and specificity for US and rapid MRI were 65.3% (95% CI: 57.5%–72.5%); 97.0% (95% CI: 94.5%–98.5%) and 98.3% (95% CI: 90.6%–100.0%); 96.1%, (95% CI: 91.1%–98.7%), respectively. US alone was associated with the shortest median ED LOS (5.3 hours, IQR 3.9–7.8), followed by rapid MRI alone (7.9 hours, IQR 5.4–8.6). US with subsequent rapid MRI was associated with the longest ED LOS (10.6 hours, IQR 7.6–13.3).

conclusionUS was nondiagnostic for a substantial number of studies performed resulting in suboptimal sensitivity for the diagnosis of appendicitis. Rapid MRI had better sensitivity but a greater LOS. Future work should focus on determining potential barriers that exist and incorporating strategies to enhance US performance and/or decrease rapid MRI LOS.

Indexed as

AppendicitisEmergency Service, HospitalMagnetic Resonance ImagingAcute DiseaseAdolescentChildChild, PreschoolFemaleHospitals, GeneralHumansLength of StayMaleRetrospective StudiesSensitivity and SpecificityUltrasonographyAcute appendicitisDiagnostic accuracyMagnetic resonance imaging (MRI)Pediatric Emergency Department (ED)Ultrasound (US)

Identifiers

PMID41733873
PMCPMC13233868

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.