ArticleEsophagus : official journal of the Japan Esophageal Society2026
Short-term outcomes of robot-assisted versus conventional thoracoscopic esophagectomy: a nationwide inpatient database study in Japan.
Article in Esophagus : official journal of the Japan Esophageal Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundAlthough the clinical application of robot-assisted esophagectomy (RE) has increased globally, its advantages over conventional thoracoscopic esophagectomy (TE) remain unclear. The aim of this study was to evaluate the short-term outcomes of RE compared with TE in patients with esophageal cancer in a nationwide cohort.
methodsWe retrospectively analyzed patients who underwent RE or TE for esophageal cancer between April 2018 and March 2022 by extracting data from the Diagnosis Procedure Combination, a Japanese national inpatient database. Instrumental variable analysis was employed to compare the short-term outcomes between the two groups. The primary outcomes included respiratory complications and unplanned reintubation.
resultsAmong 7003 eligible patients from 69 hospitals, 1971 (28.1%) and 5032 (71.9%) underwent RE and TE, respectively. Respiratory complications, unplanned reintubation, and anastomotic leakage occurred in 1501 (21.4%), 475 (6.8%), and 904 patients (12.9%), respectively. Instrumental variable analysis demonstrated that the incidence of respiratory complications [odds ratio 0.65 (95% CI: 0.52-0.81) P < 0.001], unplanned reintubation [0.44 (0.31-0.62) P < 0.001], and anastomotic leakage [0.73 (0.56-0.94) P = 0.013] was significantly lower in the RE group compared with the TE group.
conclusionsRE was associated with better short-term outcomes, including fewer respiratory complications, unplanned reintubation, and anastomotic leakage, compared with TE.
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