Evidence map›Paper›PMID 41733749›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Symptom burden and palliative care in patients with hematologic malignancies: a single-center experience.

Annasofia Holopainen, Taru Kuittinen, Kristiina Tyynelä-Korhonen, Annamarja Lamminmäki

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Annasofia HolopainenDepartment of Hematology, Kuopio University Hospital, The Wellbeing Services County of North Savo, Kuopio, Finland. Annasofia.holopainen@pshyvinvointialue.fi.
Taru KuittinenDepartment of Hematology, Kuopio University Hospital, The Wellbeing Services County of North Savo, Kuopio, Finland.
Kristiina Tyynelä-KorhonenPalliative Care Center, Päijät-Häme Wellbeing Services County, Lahti, Finland.
Annamarja LamminmäkiUniversity of Eastern Finland, Kuopio , Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with hematological malignancies are a heterogeneous group with special palliative care needs. They are known to have many symptoms and frequent emergency room visits and hospitalizations in the end-of-life phase. However, there are limited data about the symptom burden and health care service utilization in different diagnostic groups of hematological malignancies.

objectivesThe purpose of this study was to define the symptom burden and characteristics of the palliative care phase in patients with hematological malignancies in different diagnostic groups.

methodsThis retrospective study comprised 195 patients with hematological malignancies who were treated in the Kuopio University Hospital palliative care unit and died between 1.1.2015 and 31.12.2023. Patients were divided into four patient groups: myeloma, lymphoma, leukemia and myelodysplastic syndrome or myeloproliferative neoplasm (MDS/MPN).

resultsAll patient groups had a considerable symptom burden, with many emergency room visits and hospital admissions near death. Furthermore, palliative care involvement occurred late. Fatigue, pain, and dyspnea were the most common symptoms in myeloma and lymphoma patients; fatigue, pain and loss of appetite in leukemia patients and fatigue, dyspnea and depression or anxiety in MDS/MPN patients in palliative care.

conclusionPatients with hematological malignancies have a significant symptom burden and remarkable palliative care needs at the end of life. More research and awareness of the benefits of palliative care are needed.

Indexed as

Hematologic NeoplasmsPalliative CareAdultAgedAged, 80 and overEmergency Room VisitsFemaleFinlandHospitalizationHumansMaleMiddle AgedRetrospective StudiesSymptom BurdenHematologic neoplasmsHospitalizationPalliative medicineSymptomsTerminal care

Identifiers

PMID41733749
PMCPMC12932300

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.