Evidence map›Paper›PMID 41733516›Full record

ArticleJACC. Case reports2026

Debulking of the Mitral Valve: The Transseptal Approach.

Tanja Kücken, Nora Huang, Frank Hölschermann, Cornel Koban, Anja Haase-Fielitz, Michael Neuß, Christian Butter

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tanja KückenDepartment of Cardiology, University Hospital Heart Centre Brandenburg, Brandenburg Medical School Theodor Fontane, Bernau, Germany; Faculty of Health Sciences (FGW), Joint Faculty of the University of Potsdam, the Brandenburg Medical School Theodor Fontane and the Brandenburg Technical University Cottbus-Senftenberg, Cottbus, Germany. Electronic address: tanja.kuecken@immanuelalbertinen.de.
Nora HuangDepartment of Cardiology, University Hospital Heart Centre Brandenburg, Brandenburg Medical School Theodor Fontane, Bernau, Germany; Faculty of Health Sciences (FGW), Joint Faculty of the University of Potsdam, the Brandenburg Medical School Theodor Fontane and the Brandenburg Technical University Cottbus-Senftenberg, Cottbus, Germany.
Frank HölschermannDepartment of Cardiology, University Hospital Heart Centre Brandenburg, Brandenburg Medical School Theodor Fontane, Bernau, Germany; Faculty of Health Sciences (FGW), Joint Faculty of the University of Potsdam, the Brandenburg Medical School Theodor Fontane and the Brandenburg Technical University Cottbus-Senftenberg, Cottbus, Germany.
Cornel KobanDepartment of Cardiology, University Hospital Heart Centre Brandenburg, Brandenburg Medical School Theodor Fontane, Bernau, Germany; Faculty of Health Sciences (FGW), Joint Faculty of the University of Potsdam, the Brandenburg Medical School Theodor Fontane and the Brandenburg Technical University Cottbus-Senftenberg, Cottbus, Germany.
Anja Haase-FielitzDepartment of Cardiology, University Hospital Heart Centre Brandenburg, Brandenburg Medical School Theodor Fontane, Bernau, Germany; Faculty of Health Sciences (FGW), Joint Faculty of the University of Potsdam, the Brandenburg Medical School Theodor Fontane and the Brandenburg Technical University Cottbus-Senftenberg, Cottbus, Germany; Institute of Social Medicine and Health System Research, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Michael NeußDepartment of Cardiology, University Hospital Heart Centre Brandenburg, Brandenburg Medical School Theodor Fontane, Bernau, Germany; Faculty of Health Sciences (FGW), Joint Faculty of the University of Potsdam, the Brandenburg Medical School Theodor Fontane and the Brandenburg Technical University Cottbus-Senftenberg, Cottbus, Germany.
Christian ButterDepartment of Cardiology, University Hospital Heart Centre Brandenburg, Brandenburg Medical School Theodor Fontane, Bernau, Germany; Faculty of Health Sciences (FGW), Joint Faculty of the University of Potsdam, the Brandenburg Medical School Theodor Fontane and the Brandenburg Technical University Cottbus-Senftenberg, Cottbus, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with thrombotic or infective masses on native or biological mitral valve have no established treatment if deemed ineligible for surgery. This case series summarizes our initial experience with a transseptal interventional bailout approach. CASE SUMMARY: Seven high-risk patients (aged 74.0 ± 4.87 years; EuroSCORE II median 14.05%) underwent transseptal debulking under cerebral protection. Six procedures used the INARI system (FlowTriever; INARI Medical) and the TriClip system (Abbott). Debulking was technically successful in all patients, without stroke, valve injury, or relevant mitral regurgitation. In 3 patients with severe mitral stenosis (gradient 23.0 ± 2.6 mm Hg), gradients were reduced by 16.6 ± 2.1 mm Hg. DISCUSSION: Transseptal aspiration using large-bore catheters appears feasible and safe in selected nonsurgical candidates with mitral valve-adherent masses. TAKE-HOME MESSAGES: Transseptal aspiration of left-sided mitral valve-adherent masses is technically feasible in high-risk nonsurgical patients using large-bore steerable catheters and a cerebral protection system. This series suggests that thrombotic or infective masses on the mitral valve can be safely debulked through transseptal aspiration.

Indexed as

endocarditismitral valvestroketreatment

Identifiers

PMID41733516
PMCPMC13080584

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.