Evidence map›Paper›PMID 41733336›Full record

ArticleeLife2026

Non-visual light modulates behavioral memory and gene expression in

Zhijian Ji, Bingying Wang, Rashmi Chandra, Junqiang Liu, Supeng Yang, Yong Long, Michael Egan, Fujia Han, Han Wang, Noelle L'Etoile and 1 more

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Zhijian Ji *Cardiovascular Research Institute, University of California, San Francisco, San Francisco, United States.ORCID https://orcid.org/0009-0005-6314-0961
Bingying Wang *Cardiovascular Research Institute, University of California, San Francisco, San Francisco, United States.
Rashmi Chandra *Cardiovascular Research Institute, University of California, San Francisco, San Francisco, United States.
Junqiang Liu *Cardiovascular Research Institute, University of California, San Francisco, San Francisco, United States.ORCID https://orcid.org/0000-0002-2953-487X
Supeng YangCardiovascular Research Institute, University of California, San Francisco, San Francisco, United States.
Yong LongKey Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Michael EganCardiovascular Research Institute, University of California, San Francisco, San Francisco, United States.
Fujia HanDepartment of Integrative Biology, University of Wisconsin-Madison, Madison, United States.ORCID https://orcid.org/0009-0009-7079-6108
Han WangDepartment of Integrative Biology, University of Wisconsin-Madison, Madison, United States.ORCID https://orcid.org/0000-0002-1933-5762
Noelle L'EtoileDepartment of Cell and Tissue Biology, University of California, San Francisco, San Francisco, United States.
Dengke K MaCardiovascular Research Institute, University of California, San Francisco, San Francisco, United States.ORCID https://orcid.org/0000-0002-5619-7485

Funding

Genetic pathway and cellular mechanism underlying organismic responses to hypoxia and hypothermiaR35GM139618 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Dengke Ma · 2021 to 2026
$2.3M
NIGMS NIH HHS R35 GM139618NIGMS NIH HHS R35GM139618ODCDC CDC HHS P40 OD010440
6 · The paper itself

Abstract

Visible light influences a range of physiological processes, yet how animals respond to it independently of the visual system remains largely unknown. Here, we uncover a previously undescribed light-induced transcriptional pathway that modulates behavioral plasticity in

Indexed as

Behavior, AnimalCaenorhabditis elegansGene Expression RegulationLightMemoryAnimalsBlue LightCaenorhabditis elegans ProteinsCytochrome P-450 Enzyme SystemCaenorhabditis elegans ProteinsCytochrome P-450 Enzyme Systembody–brain communicationCaenorhabditis elegansCEBP-2C. eleganscell biologycytochrome P450geneticsgenomicsnon-visual phototransductionZIP-2

Identifiers

PMID41733336
PMCPMC12931922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.