Evidence map›Paper›PMID 41733132›Full record

Trial reportBritish journal of haematology2026

Invasive yeast infection in paediatric acute lymphoblastic leukaemia: A report from the multi-international clinical trial AIEOP-BFM ALL 2009.

Andreas H Groll, Simone Cesaro, Julia Alten, Andishe Attarbaschi, Draga Barbaric, Daniel Ebrahimi-Fakhari, Nicole Bodmer, Valentino Conter, Sarah Elitzur, Anja Möricke and 5 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in British journal of haematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Andreas H GrollInfectious Disease Research Program, Department of Pediatric Hematology and Oncology and Center for Bone Marrow Transplantation, University Children's Hospital Münster, Münster, Germany.ORCID https://orcid.org/0000-0003-1188-393X
Simone CesaroPaediatric Haematology Oncology, Department of Mother and Child, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.ORCID https://orcid.org/0000-0002-8698-9547
Julia AltenPediatric Hematology-Oncology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Andishe AttarbaschiSt. Anna Children's Hospital, Medical University of Vienna, Vienna, Austria.
Draga BarbaricSydney Children's Hospital, Randwick, New South Wales, Australia.
Daniel Ebrahimi-FakhariInfectious Disease Research Program, Department of Pediatric Hematology and Oncology and Center for Bone Marrow Transplantation, University Children's Hospital Münster, Münster, Germany.ORCID https://orcid.org/0000-0002-3097-141X
Nicole BodmerUniversity Children's Hospital Zurich, Zurich, Switzerland.
Valentino ConterTettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.ORCID https://orcid.org/0000-0001-5697-4929
Sarah ElitzurSchneider Children's Medical Center and Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0000-0002-3495-7578
Anja MörickePediatric Hematology-Oncology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Martin SchrappePediatric Hematology-Oncology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Jan StaryCzech Working Group for Pediatric Hematology, Prague, Czech Republic.
Ester ZapotockaDepartment of Pediatric Hematology/Oncology, University Hospital Motol, Prague, Czech Republic.
Martin ZimmermannDepartment of Pediatric Hematology/Oncology, Hannover Medical School, Hannover, Germany.
Thomas LehrnbecherDivison of Pediatric Hematology and Oncology, Department of Pediatrics, Johann Wolfgang Goethe-University, Frankfurt, Germany.

Funding

Deutsche Krebshilfe 108588
6 · The paper itself

Abstract

Prospective data of a large randomized multi-international leukaemia trial revealed an incidence of 1.1% of invasive yeast infections (IYIs) in children with acute lymphoblastic leukaemia. IYIs occurred predominantly during induction chemotherapy, presented as bloodstream infection ± tissue involvement, were due to a variety of yeast and had an attributable mortality of 5.9%.

Indexed as

Invasive Fungal InfectionsPrecursor Cell Lymphoblastic Leukemia-LymphomaAdolescentAntifungal AgentsAntineoplastic Combined Chemotherapy ProtocolsChildChild, PreschoolFemaleHumansIncidenceInduction ChemotherapyInfantMaleAntifungal AgentscancerCandidachildrenepidemiologyleukaemiamycosesoutcomeyeast

Identifiers

PMID41733132
PMCPMC13176528

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.