Evidence map›Paper›PMID 41732994›Full record

ReviewJournal of the American Heart Association2026

Management of Liver Cirrhosis in Percutaneous and Surgical Cardiac Interventions.

Cristiano Spadaccio, Antonio Nenna, Krishna Mehta, Angelo Pisani, Asishana Osho, Fernando Juarez-Casso, Domenico Alvaro, Imran Arif, Antonio Panza, Russell S Vester and 4 more

Abstract readReview
In one paragraph

Review in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Cristiano SpadaccioCardiothoracic Surgery University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0002-1672-7576
Antonio NennaCardiovascular Surgery Fondazione Policlinico Universitario Campus Bio-Medico Rome Italy.
Krishna MehtaLancaster University Lancaster UK.
Angelo PisaniCardiac Surgery Hôpital Bichat - Claude-Bernard Paris France.ORCID 0000-0002-4105-6962
Asishana OshoCardiac Surgery, Massachusetts General Hospital [MGH] - Harvard Medical School Boston MA USA.ORCID 0000-0002-1140-097X
Fernando Juarez-CassoCardiovascular Surgery Mayo Clinic Rochester MN USA.
Domenico AlvaroDepartment of Translational and Precision Medicine Sapienza University of Rome Italy.ORCID 0000-0003-3771-9644
Imran ArifCardiothoracic Surgery University of Cincinnati College of Medicine Cincinnati OH USA.
Antonio PanzaCardiothoracic Surgery University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0002-0581-5386
Russell S VesterCardiothoracic Surgery University of Cincinnati College of Medicine Cincinnati OH USA.
Louis B LouisCardiothoracic Surgery University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0003-3088-5164
Thoralf M SundtCardiac Surgery, Massachusetts General Hospital [MGH] - Harvard Medical School Boston MA USA.ORCID 0000-0002-0409-7028
Juan CrestanelloCardiovascular Surgery Mayo Clinic Rochester MN USA.ORCID 0000-0001-5415-1478
David RoseCardiothoracic Surgery University of Cincinnati College of Medicine Cincinnati OH USA.ORCID 0000-0001-7616-6283

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The systemic impairment that accompanies liver cirrhosis is known to carry a significant burden on death and postoperative complications in cardiovascular interventions. This review analyzes the impact of liver cirrhosis on short- and long-term outcomes after cardiac surgery and percutaneous procedures, providing an evidence-based guidance in the decision-making process and perioperative management of these patients. Several parameters should be considered by the heart teams when assessing eligibility, indications for intervention, and perioperative management of these patients. Life expectancy, long-term procedural outcomes, Child-Pugh or the Model for End-Stage Liver Disease score, presence of gastroesophageal varices and hepatic venous pressure gradient were extrapolated as the main determinants in decision making in patients with cirrhosis. Assessment and treatment of gastroesophageal varices is mandatory. Hepatic venous pressure gradient values >20 mm Hg preclude patients from a surgical approach. Considering the poor prognosis of advanced liver cirrhosis, futile treatments should be avoided. A multidimensional heart team approach involving surgical, cardiologic, anesthesiologic, hepatological, and medical considerations is recommended.

Indexed as

Cardiac Surgical ProceduresLiver CirrhosisPercutaneous Coronary InterventionHumansRisk FactorsTreatment Outcomecardiac surgerycirrhosisliver diseasepercutaneouspercutaneous coronary interventiontranscatheter aortic valve replacement

Identifiers

PMID41732994
PMCPMC13055755

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.