Evidence map›Paper›PMID 41732925›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026

Hysteroscopy metroplasty for partial septate uterus: Just a matter of infertility?

Alessandro Arena, Agnese Virgilio, Camilla Franceschini, Erika Bettiol, Pierandrea De Benedetti, Roberto Sardina, Giulia Cincotta, Eugenia Mantovani, Renato Seracchioli, Paolo Casadio

Abstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Hysteroscopy metroplasty for partial septate uterus: Just a matter of infertility?International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alessandro ArenaDivision of Gynaecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero - University of Bologna, Bologna, Italy.
Agnese VirgilioUnit of Gynecology, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Camilla FranceschiniDepartment of Gynecological and Obstetric, San Luca Hospital, Lucca, Italy.
Erika BettiolDivision of Gynaecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero - University of Bologna, Bologna, Italy.ORCID https://orcid.org/0009-0002-0188-1332
Pierandrea De BenedettiDivision of Gynaecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero - University of Bologna, Bologna, Italy.
Roberto SardinaDivision of Gynaecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero - University of Bologna, Bologna, Italy.
Giulia CincottaDivision of Gynaecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero - University of Bologna, Bologna, Italy.
Eugenia MantovaniDivision of Gynaecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero - University of Bologna, Bologna, Italy.
Renato SeracchioliDivision of Gynaecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero - University of Bologna, Bologna, Italy.
Paolo CasadioDivision of Gynaecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero - University of Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe primary objective of this study is to assess the impact of hysteroscopic metroplasty on symptom relief, including dysmenorrhea, dyspareunia, and menstrual blood flow in women with partial uterine septa (U2a class). Additionally, the study aims to investigate potential correlations between clinical and ultrasonographic characteristics and changes in these symptoms.

methodsThis was a prospective cohort study conducted at a single center, enrolling women who underwent hysteroscopic metroplasty between March 2022 and September 2023. Participants presented with dysmenorrhea, dyspareunia, and abnormal menstrual blood flow and had expressed a desire for pregnancy. Preoperative symptom severity was measured using a visual analog scale, ranging from 0 to 100. Preoperative three-dimensional transvaginal ultrasonography was performed to assess septal characteristics. A 12-month follow-up was conducted to evaluate changes in symptoms postoperatively. Exclusion criteria included alternative causes of pelvic pain, incomplete septum correction necessitating further surgery, and pregnancy or hormonal therapy within 12 months prior to or following the surgery.

resultsA total of 52 symptomatic patients with U2a uterine septa underwent hysteroscopic metroplasty, and data from 44 patients were analyzed according to the inclusion and exclusion criteria. Postoperative assessments revealed a significant reduction in dysmenorrhea (mean ± standard deviation: 50.2 ± 20.5 vs. 33.1 ± 20.4, P < 0.001) and dyspareunia (mean ± standard deviation: 41.4 ± 9.5 vs. 28.6 ± 24.5, P < 0.028). However, no significant changes were observed in menstrual blood flow.

conclusionHysteroscopic metroplasty in patients with partial uterine septa results in significant symptom relief, particularly for dysmenorrhea and dyspareunia. These findings underscore the potential benefits of metroplasty beyond reproductive outcomes. Further large-scale studies are necessary to confirm these results.

Indexed as

HysteroscopySeptate UterusUterusAdultDysmenorrheaDyspareuniaFemaleHumansInfertility, FemaleProspective StudiesTreatment OutcomeUltrasonographyhysteroscopymetroplastyMüllerian anomaliesquality of lifeseptate uterussymptoms relief

Identifiers

PMID41732925
PMCPMC13377344

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.