ReviewComprehensive reviews in food science and food safety2026
Encapsulation and Functional Activity of Lactobacillus reuteri Strains: Advances, Challenges, and Perspectives.
Review in Comprehensive reviews in food science and food safety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Bioadhesive Alginate/Chitosan Hydrogels for Sustained Probiotic Delivery and Enhanced Antibacterial Treatment of Oral Ulcers.Gels (Basel, Switzerland) · 2026Article
- Polymer-Based and Biomaterial Encapsulation of Probiotics for Improved Viability.Probiotics and antimicrobial proteins · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past decade, probiotics have gone from been special health supplements to widely incorporated components in many foods and nutrition products. This has led to more careful checks of their safety, viability, and functional performance under realistic processing and consumption conditions. Within lactic acid bacteria, Limosilactobacillus reuteri (formerly Lactobacillus reuteri) has been extensively investigated for its immunomodulatory, antimicrobial, anti-inflammatory, antioxidant, and metabolic properties as demonstrated across multiple in vivo and in vitro experimental models. Despite these functional attributes, its viability during food processing and gastrointestinal transit remains strongly influenced by the strain and the characteristics of the delivery matrix; as a result, encapsulation is an essential strategy to preserve cellular integrity and functionality. The present review examines the functional properties of Limosilactobacillus reuteri (L. reuteri or LR) strains alongside the technological approaches used for their encapsulation. Current encapsulation approaches, including ionic gelation, extrusion, electrospray, and spray drying combined with biopolymers to improve encapsulation efficiency and survival of strains such as DSM 17938 and DSM 20016, are discussed with emphasis on their applicability to probiotic delivery and the formulation of functional foods with potential to improve gastrointestinal health, modulate inflammation, and enhance metabolic functions. In addition to strain-specific functional activities, this review examines how coating material, processing method, and strain affect release kinetics, functional activities, and viability. However, data on the stability of encapsulated L. reuteri during industrial processing, storage, and health claim validation under regulatory frameworks remain limited. Future research should address these challenges to support the use of L. reuteri in functional foods and therapeutic products.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.