Evidence map›Paper›PMID 41732728›Full record

ArticlePeerJ2026

Altered anterior segment biometrics in cataract patients with retinitis pigmentosa: a propensity-matched analysis suggests patterns of zonular weakness.

Yonglin Chen, Zhiheng Lian, Yongguo Xiang, Hong Cheng, Chong Tang, Yanlin Yang, Liang Liang, Juan Kang, Ke Hu, Shijie Zheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Yonglin ChenThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocul, Chong Qing, China.
Zhiheng LianThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocul, Chong Qing, China.
Yongguo XiangThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocul, Chong Qing, China.
Hong ChengThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocul, Chong Qing, China.
Chong TangThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocul, Chong Qing, China.
Yanlin YangThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocul, Chong Qing, China.
Liang LiangChangdu People's Hospital of Xizang, Tibet, Qamdo, China.
Juan KangChangdu People's Hospital of Xizang, Tibet, Qamdo, China.
Ke HuThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocul, Chong Qing, China.
Shijie ZhengThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Prevention and Treatment on Major Blinding Diseases, Chongqing Eye Institute, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocul, Chong Qing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To explore the spatial structure of the anterior segment biometrics in cataract patients with retinitis pigmentosa (RP). Methods: This is a retrospective study. We conducted a propensity score matching analysis (1:3) on anterior segment data of RP patients and normal cataract patients who underwent cataract surgery from August 2023 to February 2025. Baseline variables (age, gender, axial length, and Pentacam Nucleus Staging (PNS) score) were balanced to compare the differences in anterior segment biometric measurements between the two groups. Results: We analyzed the anterior segment data of 37 cataract patients with RP and 102 simple cataract patients. The RP group exhibited a thicker lens ( Discussions: RP patients exhibit a thicker lens, a more anteriorly positioned lens, shallower anterior chamber depth, and greater corneal astigmatism. These changes can be explained by zonular weakness. Decision-making surrounding intraocular lens selection in eyes with RP, cataract, and zonular compromise may be enhanced through proper identification of preoperative biometric irregularities in the anterior segment.

Indexed as

Anterior Eye SegmentCataractRetinitis PigmentosaAdultAgedBiometryCataract ExtractionFemaleHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesAnterior segment biometricsCataractRetinitis pigmentosaZonule

Identifiers

PMID41732728
PMCPMC12925417

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.