ArticleCureus2026
Declining Diagnostic Accuracy of the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) Score in Necrotizing Fasciitis: A Case Report With Contemporary Evidence Review.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Necrotizing fasciitis is a rapidly advancing soft-tissue infection with high morbidity and mortality, and markedly worse prognosis when complicated by delayed diagnosis and intervention. Distinguishing necrotizing fasciitis from less severe soft-tissue infections remains a significant clinical challenge, prompting the development of the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score to aid early recognition. Early enthusiasm for the score led to widespread clinical use; however, subsequent experience has raised concerns about its utility as a sensitive rule-out tool. We present a case of surgically confirmed necrotizing fasciitis in which the LRINEC score failed to appropriately categorize the condition as high risk at presentation, prompting a focused investigation of evolving LRINEC literature. This case and accompanying review highlight the limitations of the LRINEC score as an isolated rule-out diagnostic instrument and support its more adjunctive role to clinical judgement, physical examination, imaging, and early surgical consultation. A high index of suspicion combined with conscientious implementation of comprehensive and inclusive diagnostic utilities can avoid delays in diagnosis and promote improved outcomes while modified and novel diagnostic applications are investigated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.