Evidence map›Paper›PMID 41732578›Full record

ReviewCJC open2026

Rheumatic Heart Disease: Global Failure in Tackling a Common Killer.

Valdano Manuel, Ana Olga Mocumbi, Liesl Zühlke

Abstract readReview
In one paragraph

Review in CJC open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Valdano ManuelCardiovascular and Thoracic Service, Complexo Hospitalar de Doenças Cardio-Pulmonares Cardeal Dom Alexandre do Nascimento, Luanda, Angola.
Ana Olga MocumbiInstituto Nacional de Saúde, Maputo, Mozambique.
Liesl ZühlkeSouth African Medical Research Council, Parow, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatic heart disease (RHD) remains a major cause of preventable morbidity and premature death, affecting over 40 million people worldwide and causing more than 300,000 deaths annually, predominantly in low- and middle-income countries. Children and adolescents bear a substantial burden, with 1-year mortality rates up to 17%, primarily from heart failure, especially among those with poor adherence to benzathine penicillin prophylaxis. RHD is entirely preventable through timely diagnosis and secondary prophylaxis, yet access to prevention, medical therapy, and surgical care remains inconsistent. Girls and women face delayed diagnosis, high maternal mortality, and inequitable access to gender-sensitive care. Fewer than 10 African countries have implemented national or pilot RHD programs, and despite the 2018 World Health Assembly Resolution 71.14, progress remains slow. Sustainable, African-led programs integrated into national healthcare systems are urgently needed to reduce RHD-related mortality and achieve its long-term elimination.

Indexed as

Africaglobal access initiativesRheumatic heart disease

Identifiers

PMID41732578
PMCPMC12925792

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.