Evidence map›Paper›PMID 41732386›Full record

ArticleMaterials today. Bio2026

Exploring immobilization strategies of antimicrobial peptides onto MAO-treated titanium to fight MRSA colonization and preserve osteogenic activity.

Natália A Costa, Cláudia Monteiro, Liliana Grenho, Ana R Ribeiro, Victoria Leiro, Maria H Fernandes, Paulo N Lisboa-Filho, M Cristina L Martins

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In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Natália A CostaUNESP - Universidade Estadual Paulista, Faculdade de Ciências, Bauru, SP, 17033-360, Brazil.
Cláudia Monteiroi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, 4200-135, Portugal.
Liliana GrenhoBoneLab, Faculdade de Medicina Dentária, Universidade do Porto, Rua Dr. Manuel Pereira da Silva, Porto, 4200-393, Portugal.
Ana R RibeiroNanoSafety Group, International Iberian Nanotechnology Laboratory, Braga, 4715-330, Portugal.
Victoria Leiroi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, 4200-135, Portugal.
Maria H FernandesBoneLab, Faculdade de Medicina Dentária, Universidade do Porto, Rua Dr. Manuel Pereira da Silva, Porto, 4200-393, Portugal.
Paulo N Lisboa-FilhoUNESP - Universidade Estadual Paulista, Faculdade de Ciências, Bauru, SP, 17033-360, Brazil.
M Cristina L Martinsi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, 4200-135, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alternative therapies to systemic antibiotics are increasingly explored to prevent infections associated with bone implants. Among them, the surface functionalization of titanium with antimicrobial peptides (AMP) is particularly promising due to their broad-spectrum activity and low risk of inducing bacterial resistance. However, a critical challenge remains in achieving both effective antibacterial action and the promotion of osseointegration. This proof-of-concept study investigates different strategies for immobilizing AMP onto bioactive micro-arc oxidation (MAO) coatings on titanium, aiming to combat methicillin-resistant

Indexed as

Antimicrobial peptides immobilizationBone-like cellsMethicillin-resistant Staphylococcus aureusMicro-arc oxidationSurface functionalizationTitanium

Identifiers

PMID41732386
PMCPMC12924753

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.