Evidence map›Paper›PMID 41732326›Full record

ArticleTherapeutic advances in gastroenterology2026

Digital cholangioscope-assisted endoscopic direct-vision appendicitis therapy versus laparoscopic appendectomy for chronic appendicitis: a multicenter retrospective cohort study.

Lu Chen, Yadong Feng, Yang Liu, Zhi Wang, Qin Lu, Lihua Ren, Juan Liu, Kaizhe Yang, Li Xu, Xin Yin and 1 more

Abstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lu ChenDepartment of Gastroenterology, Zhongda Hospital Southeast University, Nanjing, China.ORCID https://orcid.org/0000-0002-2411-6935
Yadong FengDepartment of Gastroenterology, Zhongda Hospital Southeast University, Nanjing, China.
Yang LiuDepartment of Gastroenterology, Liangjiang Hospital Southeast University, Nanjing, China.
Zhi WangDepartment of Gastroenterology, Zhongda Hospital Southeast University, Nanjing, China.
Qin LuDepartment of Gastroenterology, Zhongda Hospital Southeast University, Nanjing, China.ORCID https://orcid.org/0000-0002-9015-9984
Lihua RenDepartment of Gastroenterology, Zhongda Hospital Southeast University, Nanjing, China.ORCID https://orcid.org/0000-0003-1726-3686
Juan LiuDepartment of Gastroenterology, Zhongda Hospital Southeast University, Nanjing, China.
Kaizhe YangSchool of Medicine, Southeast University, Nanjing, China.
Li XuSchool of Medicine, Southeast University, Nanjing, China.
Xin YinDepartment of Gastroenterology, Affiliated Changshu Hospital of Nantong University, Suzhou, Jiangsu, China.
Ruihua ShiDepartment of Gastroenterology, Zhongda Hospital Southeast University, Nanjing 210009, China Department of Gastroenterology, Liangjiang Hospital Southeast University, Nanjing 211800, China.ORCID https://orcid.org/0000-0003-4977-8801

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Laparoscopic appendectomy (LA) is the conventional treatment for chronic appendicitis. Endoscopic direct-vision appendicitis therapy (EDAT) has emerged as a minimally invasive, organ-preserving alternative. Objectives: To compare the efficacy and safety of EDAT versus LA in chronic appendicitis. Design: Multicenter retrospective cohort study with propensity score matching (PSM). Methods: This multicenter retrospective cohort study was conducted in China between January 2019 and February 2024. PSM was performed to minimize selection bias. A total of 186 patients with chronic appendicitis were included, including 63 who received EDAT and 123 who underwent LA. The primary outcome was the clinical success rate. The secondary outcomes included the technical success rate, duration of hospitalization, adverse event rate, and recurrence rate. Results: Compared with LA, EDAT showed comparable clinical success (95.2% vs 100%, Conclusion: Compared with LA, EDAT is a safe, effective, organ-preserving alternative technique for chronic appendicitis, offering a shorter recovery time, reduced adverse event rates, and a low recurrence rate observed during follow-up.

Indexed as

adverse eventschronic appendicitisdirect visualizationlaparoscopic appendectomyorgan-preserving therapy

Identifiers

PMID41732326
PMCPMC12924964

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.