ArticleAmerican heart journal plus : cardiology research and practice2026
Symptom experience of women with ischemia and no obstructive coronary artery disease: A mixed-methods approach.
Article in American heart journal plus : cardiology research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Women with myocardial ischemia with no obstructive arteries (INOCA) often have coronary microvascular dysfunction (CMD) or coronary vasospasm. INOCA is associated with adverse cardiovascular event risk, recurrent angina hospitalizations, and reduced health-related quality of life (QoL). Objectives: In this mixed-methods study we used qualitative data to understand angina burden, while considering overall symptom experience of patients living with INOCA. Methods: Twenty-four women with INOCA confirmed by coronary angiography were enrolled. A majority ( Results: Mean age was 53.2 ± 10.8 years and body mass index was 30.8 ± 6.9 kg/m Conclusions: This study highlights the substantial emotional and physical challenges women living with INOCA experience, emphasizing critical care gaps. Research efforts should prioritize understanding pathophysiologic mechanisms and improving symptom management to better support patient QoL.
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