ReviewJournal of translational autoimmunity2026
Extracellular vesicles and their role in Lupus Nephritis: A scoping review.
Review in Journal of translational autoimmunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Urinary Extracellular Vesicles Biomarkers in CKD: Clinical Laboratory Translation.Diagnostics (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lupus nephritis (LN) is one of the most severe and common complications of systemic lupus erythematosus (SLE), which pathogenesis is mainly driven by immune complex deposition and infiltration of immune cells, ultimately leading to progressive renal damage. Extracellular vesicles (EVs) are nanometer-sized particles released by almost all cell types that mediate intercellular communication and modulate diverse biological processes, including immune activation, through the transfer of vesicular cargo. Increasing evidence shows that EVs contribute significantly to the pathogenesis of LN, mediating processes such as antigen presentation, stimulating inflammatory cytokine production and facilitating immune complex deposition, among other mechanisms. Following this line of thought, EVs represent a promising source of specific biomarkers for early diagnosis, monitoring of disease activity and even development of therapeutic targets. This review focuses on summarizing the most recent findings on the role of EVs in LN pathophysiology, diagnosis, monitoring, and their potential for the development of therapeutic solutions.
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Registered trials
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